Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene.

Takechi, Tomoki; Hirota, Takeshi; Sakai, Tatsuya; Maeda, Natsumi; Kobayashi, Daisuke; Ieiri, Ichiro

Takechi, Tomoki; Hirota, Takeshi; Sakai, Tatsuya; Maeda, Natsumi; Kobayashi, Daisuke; Ieiri, Ichiro.

Afiliación

Takechi T; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan (T.T., T.H., T.S., N.M., I.I.); Drug Development Research Laboratories, Kyoto R&D Center, Maruho Co., Ltd., Kyoto, Japan (T.T.); and Department of Clinical Pharmacy and Pharmace
Hirota T; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan (T.T., T.H., T.S., N.M., I.I.); Drug Development Research Laboratories, Kyoto R&D Center, Maruho Co., Ltd., Kyoto, Japan (T.T.); and Department of Clinical Pharmacy and Pharmace
Sakai T; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan (T.T., T.H., T.S., N.M., I.I.); Drug Development Research Laboratories, Kyoto R&D Center, Maruho Co., Ltd., Kyoto, Japan (T.T.); and Department of Clinical Pharmacy and Pharmace
Maeda N; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan (T.T., T.H., T.S., N.M., I.I.); Drug Development Research Laboratories, Kyoto R&D Center, Maruho Co., Ltd., Kyoto, Japan (T.T.); and Department of Clinical Pharmacy and Pharmace
Kobayashi D; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan (T.T., T.H., T.S., N.M., I.I.); Drug Development Research Laboratories, Kyoto R&D Center, Maruho Co., Ltd., Kyoto, Japan (T.T.); and Department of Clinical Pharmacy and Pharmace
Ieiri I; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan (T.T., T.H., T.S., N.M., I.I.); Drug Development Research Laboratories, Kyoto R&D Center, Maruho Co., Ltd., Kyoto, Japan (T.T.); and Department of Clinical Pharmacy and Pharmace

Drug Metab Dispos ; 46(5): 628-635, 2018 05.

Article en En | MEDLINE | ID: mdl-29437875

Asunto(s)

Metilación de ADN/genética; Proteínas Asociadas a Resistencia a Múltiples Medicamentos/genética; Piel/metabolismo; Transcripción Genética/genética; Adenosina Trifosfato/genética; Adulto; Transporte Biológico/genética; Islas de CpG/genética; Expresión Génica/genética; Humanos; Proteínas de Transporte de Membrana/genética; Persona de Mediana Edad; Transportadores de Ácidos Monocarboxílicos/genética; Polimorfismo de Nucleótido Simple/genética; Regiones Promotoras Genéticas/genética; ARN Mensajero/genética; Adulto Joven

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piel / Transcripción Genética / Metilación de ADN / Proteínas Asociadas a Resistencia a Múltiples Medicamentos Límite: Adult / Humans / Middle aged Idioma: En Revista: Drug Metab Dispos Asunto de la revista: FARMACOLOGIA Año: 2018 Tipo del documento: Article

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