SESN2 negatively regulates cell proliferation and casein synthesis by inhibition the amino acid-mediated mTORC1 pathway in cow mammary epithelial cells.

Luo, Chaochao; Zhao, Shengguo; Zhang, Muchen; Gao, Yanan; Wang, Jiaqi; Hanigan, Mark D; Zheng, Nan

Luo, Chaochao; Zhao, Shengguo; Zhang, Muchen; Gao, Yanan; Wang, Jiaqi; Hanigan, Mark D; Zheng, Nan.

Afiliación

Luo C; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, PR China.
Zhao S; Milk Risk Assessment Laboratory of Ministry of Agriculture, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, PR China.
Zhang M; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, PR China.
Gao Y; Milk Risk Assessment Laboratory of Ministry of Agriculture, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, PR China.
Wang J; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, PR China.
Hanigan MD; Milk Risk Assessment Laboratory of Ministry of Agriculture, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, PR China.
Zheng N; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, PR China.

Sci Rep ; 8(1): 3912, 2018 03 02.

Article en En | MEDLINE | ID: mdl-29500367

Asunto(s)

Aminoácidos/farmacología; Caseínas/metabolismo; Proliferación Celular; Células Epiteliales/citología; Glándulas Mamarias Animales/citología; Diana Mecanicista del Complejo 1 de la Rapamicina/metabolismo; Proteínas Nucleares/metabolismo; Animales; Bovinos; Células Cultivadas; Células Epiteliales/efectos de los fármacos; Células Epiteliales/metabolismo; Femenino; Glándulas Mamarias Animales/efectos de los fármacos; Glándulas Mamarias Animales/metabolismo; Diana Mecanicista del Complejo 1 de la Rapamicina/genética; Proteínas Nucleares/genética; Fosforilación; Transducción de Señal

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Caseínas / Proliferación Celular / Células Epiteliales / Diana Mecanicista del Complejo 1 de la Rapamicina / Aminoácidos / Glándulas Mamarias Animales Límite: Animals Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article

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