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Synthesis of novel 17-triazolyl-androst-5-en-3-ol epimers via Cu(I)-catalyzed azide-alkyne cycloaddition and their inhibitory effect on 17α-hydroxylase/C17,20-lyase.
Kiss, Anita; Herman, Bianka Edina; Görbe, Tamás; Mernyák, Erzsébet; Molnár, Barnabás; Wölfling, János; Szécsi, Mihály; Schneider, Gyula.
Afiliación
  • Kiss A; Department of Organic Chemistry, University of Szeged, Dóm tér 8., H-6720 Szeged, Hungary.
  • Herman BE; 1st Department of Medicine, University of Szeged, Korányi fasor 8-10., H-6720 Szeged, Hungary.
  • Görbe T; Organic Chemistry, Arrhenius Laboratory, Stockholm University, 106 91 Stockholm, Sweden.
  • Mernyák E; Department of Organic Chemistry, University of Szeged, Dóm tér 8., H-6720 Szeged, Hungary.
  • Molnár B; Department of Organic Chemistry, University of Szeged, Dóm tér 8., H-6720 Szeged, Hungary.
  • Wölfling J; Department of Organic Chemistry, University of Szeged, Dóm tér 8., H-6720 Szeged, Hungary.
  • Szécsi M; 1st Department of Medicine, University of Szeged, Korányi fasor 8-10., H-6720 Szeged, Hungary.
  • Schneider G; Department of Organic Chemistry, University of Szeged, Dóm tér 8., H-6720 Szeged, Hungary. Electronic address: schneider@chem.u-szeged.hu.
Steroids ; 135: 79-91, 2018 07.
Article en En | MEDLINE | ID: mdl-29577953
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Azidas / Esteroide 17-alfa-Hidroxilasa / Cobre / Alquinos / Androstenoles / Liasas Idioma: En Revista: Steroids Año: 2018 Tipo del documento: Article País de afiliación: Hungria
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Azidas / Esteroide 17-alfa-Hidroxilasa / Cobre / Alquinos / Androstenoles / Liasas Idioma: En Revista: Steroids Año: 2018 Tipo del documento: Article País de afiliación: Hungria