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Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase.
McBrayer, Samuel K; Olenchock, Benjamin A; DiNatale, Gabriel J; Shi, Diana D; Khanal, Januka; Jennings, Rebecca B; Novak, Jesse S; Oser, Matthew G; Robbins, Alissa K; Modiste, Rebecca; Bonal, Dennis; Moslehi, Javid; Bronson, Roderick T; Neuberg, Donna; Nguyen, Quang-De; Signoretti, Sabina; Losman, Julie-Aurore; Kaelin, William G.
Afiliación
  • McBrayer SK; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215.
  • Olenchock BA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215.
  • DiNatale GJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142.
  • Shi DD; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Khanal J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215.
  • Jennings RB; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215.
  • Novak JS; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215.
  • Oser MG; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215.
  • Robbins AK; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Modiste R; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215.
  • Bonal D; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Moslehi J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215.
  • Bronson RT; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215.
  • Neuberg D; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, MA 02210.
  • Nguyen QD; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, MA 02210.
  • Signoretti S; Division of Cardiovascular Medicine, Department of Medicine, School of Medicine, Vanderbilt University, Nashville, TN 37235.
  • Losman JA; Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02215.
  • Kaelin WG; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
Proc Natl Acad Sci U S A ; 115(16): E3741-E3748, 2018 04 17.
Article en En | MEDLINE | ID: mdl-29610306

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Hipofisarias / Neoplasias de la Tiroides / Proteína de Retinoblastoma / Código de Histonas / Proteínas de Unión al ADN / Histona Demetilasas con Dominio de Jumonji / Terapia Molecular Dirigida / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Hipofisarias / Neoplasias de la Tiroides / Proteína de Retinoblastoma / Código de Histonas / Proteínas de Unión al ADN / Histona Demetilasas con Dominio de Jumonji / Terapia Molecular Dirigida / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article