Fast and simple determination and exposure assessment of bisphenol A, phenol, p-tert-butylphenol, and diphenylcarbonate transferred from polycarbonate food-contact materials to food simulants.
Chemosphere
; 203: 300-306, 2018 Jul.
Article
en En
| MEDLINE
| ID: mdl-29625319
Polycarbonate (PC) plastics find extensive use in baby bottles, food storage containers, and various kitchen items. Possibly hazardous chemicals, bisphenol A (BPA), phenol, p-tert-butylphenol (TBP), and diphenylcarbonate (DPC), are source materials or by-products from PC production. Therefore, a fast and simple analytical method was developed to determine and assess the exposure of BPA, phenol, TBP, and DPC transferred from PC food-contact materials to four different food simulants (water, 4% acetic acid, 50% ethanol, and n-heptane) at different temperatures. The method was validated in terms of limit of detection (LOD) and quantification (LOQ), recovery, and precision for the detection of BPA, phenol, and TBP using HPLC-FLD and of DPC using HPLC-UV. BPA, phenol, TBP, and DPC concentrations transferred from 200â¯PC samples to food simulants were determined. The highest migration levels of BPA (54.3⯵gâ¯L-1) and phenol (43.8⯵gâ¯L-1) were found in 50% ethanol at 70⯰C. TBP did not migrate to any simulant. DPC did not show any migration from PC samples into water and only migrated from a cup to 4% acetic acid at 70⯰C and 100⯰C, whereas migration occurred from several cups, ladles, spoons, and tongs to 50% ethanol and to n-heptane at 25⯰C. Food simulants and temperature were the crucial factors for the migration of BPA and phenol from PC samples. Estimated daily intakes (EDIs), based on food consumption and food-type distribution factors, for BPA, phenol, and DPC were calculated to be 0.007, 0.001, and 2.5â¯×â¯10-4⯵gâ¯kg-1 bw day-1, respectively.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Fenoles
/
Compuestos de Bencidrilo
/
Contaminación de Alimentos
/
Fenol
/
Exposición a Riesgos Ambientales
Límite:
Humans
/
Infant
Idioma:
En
Revista:
Chemosphere
Año:
2018
Tipo del documento:
Article