F-18 FDG PET, CT, and MRI for detecting the malignant potential in patients with gastrointestinal stromal tumors: A protocol for a network meta-analysis of diagnostic test accuracy.
Medicine (Baltimore)
; 97(16): e0389, 2018 Apr.
Article
en En
| MEDLINE
| ID: mdl-29668594
ABSTRACT
BACKGROUND:
Gastrointestinal stromal tumor (GIST) is a rare cancer in gastrointestinal carcinomas and has been widely known as a curable disease among all the digestive tumors. However, early detection of malignant potential in patients with GIST has still been a huge challenge all around the world. CT, MRI, and F-18 FDG PET are all considered as good tests for diagnosing malignant GIST efficiently, but no recommended suggestions presents which test among the 3 is the prior one in detecting the malignant potential of GIST. We perform this study to assess the accuracy between CT, MRI, and F-18 FDG PET through network meta-analysis method, and to rank these tests. METHODS ANDANALYSIS:
PubMed, EMBASE.com, CNKI, and CBM databases will be searched without search date and language restrictions. We will include diagnostic tests which assessed the accuracy of CT, MRI, and F-18 FDG PET in detecting the malignant potential of GIST. The risk of bias in each study will be independently assessed as low, moderate, or high using criteria adapted from Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2). Meta-analysis will be performed using STATA 12.0 and R 3.4.1 software. The competing diagnostic tests will be ranked by a superiority index.RESULTS:
This study is ongoing, and will be submitted to a peer-reviewed journal for publication.CONCLUSION:
This study will provide a comprehensive evidence summary of CT, MRI, and F-18 FDG PET in detecting the malignant potential of GIST.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Imagen por Resonancia Magnética
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Tomografía Computarizada por Rayos X
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Fluorodesoxiglucosa F18
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Tumores del Estroma Gastrointestinal
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Tomografía de Emisión de Positrones
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Neoplasias Gastrointestinales
Tipo de estudio:
Diagnostic_studies
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Guideline
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Screening_studies
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Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Medicine (Baltimore)
Año:
2018
Tipo del documento:
Article
País de afiliación:
China