Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies-T Cell Receptor-Induced CYLD Phosphorylation by IKKÎµ/TBK1 as a Case Study.

Lork, Marie; Kreike, Marja; Staal, Jens; Beyaert, Rudi

Lork, Marie; Kreike, Marja; Staal, Jens; Beyaert, Rudi.

Afiliación

Lork M; Unit of Molecular Signal Transduction in Inflammation, Department of Biomedical Molecular Biology, VIB-UGent Center for Inflammation Research, Ghent University, Ghent, Belgium.
Kreike M; Unit of Molecular Signal Transduction in Inflammation, Department of Biomedical Molecular Biology, VIB-UGent Center for Inflammation Research, Ghent University, Ghent, Belgium.
Staal J; Unit of Molecular Signal Transduction in Inflammation, Department of Biomedical Molecular Biology, VIB-UGent Center for Inflammation Research, Ghent University, Ghent, Belgium.
Beyaert R; Unit of Molecular Signal Transduction in Inflammation, Department of Biomedical Molecular Biology, VIB-UGent Center for Inflammation Research, Ghent University, Ghent, Belgium.

Front Cell Dev Biol ; 6: 40, 2018.

Article en En | MEDLINE | ID: mdl-29755980

Palabras clave

CYLD; IKKÎµ; T cell receptor; TBK1; antibodies; kinase inhibitor; phosphorylation

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Cell Dev Biol Año: 2018 Tipo del documento: Article País de afiliación: Bélgica

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google