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Perivascular Adipose Tissue-Derived PDGF-D Contributes to Aortic Aneurysm Formation During Obesity.
Zhang, Ze-Bei; Ruan, Cheng-Chao; Lin, Jing-Rong; Xu, Lian; Chen, Xiao-Hui; Du, Ya-Nan; Fu, Meng-Xia; Kong, Ling-Ran; Zhu, Ding-Liang; Gao, Ping-Jin.
Afiliación
  • Zhang ZB; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
  • Ruan CC; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China gaopingjin@sibs.ac.cn ccruan@sibs.ac.cn.
  • Lin JR; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
  • Xu L; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
  • Chen XH; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
  • Du YN; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
  • Fu MX; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
  • Kong LR; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
  • Zhu DL; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
  • Gao PJ; The State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Department of Hypertension, Ruijin Hospital and Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China gaopingjin@sibs.ac.cn ccruan@sibs.ac.cn.
Diabetes ; 67(8): 1549-1560, 2018 08.
Article en En | MEDLINE | ID: mdl-29794241
Asunto(s)
Aorta Abdominal/metabolismo; Aneurisma de la Aorta Abdominal/etiología; Grasa Intraabdominal/metabolismo; Linfocinas/metabolismo; Obesidad/fisiopatología; Factor de Crecimiento Derivado de Plaquetas/metabolismo; Adventicia/efectos de los fármacos; Adventicia/inmunología; Adventicia/metabolismo; Adventicia/patología; Angiotensina II/administración & dosificación; Angiotensina II/efectos adversos; Animales; Aorta Abdominal/diagnóstico por imagen; Aorta Abdominal/efectos de los fármacos; Aorta Abdominal/patología; Aneurisma de la Aorta Abdominal/diagnóstico por imagen; Aneurisma de la Aorta Abdominal/metabolismo; Aneurisma de la Aorta Abdominal/patología; Bencimidazoles/farmacología; Células Cultivadas; Dieta Alta en Grasa/efectos adversos; Implantes de Medicamentos; Regulación de la Expresión Génica/efectos de los fármacos; Mediadores de Inflamación/metabolismo; Grasa Intraabdominal/efectos de los fármacos; Grasa Intraabdominal/inmunología; Grasa Intraabdominal/patología; Linfocinas/agonistas; Linfocinas/antagonistas & inhibidores; Linfocinas/genética; Masculino; Ratones; Ratones Mutantes; Ratones Transgénicos; Obesidad/etiología; Obesidad/metabolismo; Obesidad/patología; Especificidad de Órganos; Factor de Crecimiento Derivado de Plaquetas/agonistas; Factor de Crecimiento Derivado de Plaquetas/antagonistas & inhibidores; Factor de Crecimiento Derivado de Plaquetas/genética; Quinolinas/farmacología; Proteínas Recombinantes/química; Proteínas Recombinantes/metabolismo; Grasa Subcutánea Abdominal/efectos de los fármacos; Grasa Subcutánea Abdominal/inmunología; Grasa Subcutánea Abdominal/metabolismo; Grasa Subcutánea Abdominal/patología; Análisis de Supervivencia
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Aorta Abdominal / Factor de Crecimiento Derivado de Plaquetas / Linfocinas / Aneurisma de la Aorta Abdominal / Grasa Intraabdominal / Obesidad Tipo de estudio: Etiology_studies Idioma: En Revista: Diabetes Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Aorta Abdominal / Factor de Crecimiento Derivado de Plaquetas / Linfocinas / Aneurisma de la Aorta Abdominal / Grasa Intraabdominal / Obesidad Tipo de estudio: Etiology_studies Idioma: En Revista: Diabetes Año: 2018 Tipo del documento: Article