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Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release.
Szot, Christopher; Saha, Saurabh; Zhang, Xiaoyan M; Zhu, Zhongyu; Hilton, Mary Beth; Morris, Karen; Seaman, Steven; Dunleavey, James M; Hsu, Kuo-Sheng; Yu, Guo-Jun; Morris, Holly; Swing, Deborah A; Haines, Diana C; Wang, Yanping; Hwang, Jennifer; Feng, Yang; Welsch, Dean; DeCrescenzo, Gary; Chaudhary, Amit; Zudaire, Enrique; Dimitrov, Dimiter S; St Croix, Brad.
Afiliación
  • Szot C; Tumor Angiogenesis Unit, Mouse Cancer Genetics Program (MCGP), National Cancer Institute (NCI), NIH, Frederick, Maryland, USA.
  • Saha S; BioMed Valley Discoveries Inc., Kansas City, Missouri, USA.
  • Zhang XM; BioMed Valley Discoveries Inc., Kansas City, Missouri, USA.
  • Zhu Z; Tumor Angiogenesis Unit, Mouse Cancer Genetics Program (MCGP), National Cancer Institute (NCI), NIH, Frederick, Maryland, USA.
  • Hilton MB; Protein Interactions Section, Cancer and Inflammation Program, NCI, NIH, Frederick, Maryland, USA.
  • Morris K; Tumor Angiogenesis Unit, Mouse Cancer Genetics Program (MCGP), National Cancer Institute (NCI), NIH, Frederick, Maryland, USA.
  • Seaman S; Basic Research Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research (FNLCR), Frederick, Maryland, USA.
  • Dunleavey JM; Tumor Angiogenesis Unit, Mouse Cancer Genetics Program (MCGP), National Cancer Institute (NCI), NIH, Frederick, Maryland, USA.
  • Hsu KS; Basic Research Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research (FNLCR), Frederick, Maryland, USA.
  • Yu GJ; Tumor Angiogenesis Unit, Mouse Cancer Genetics Program (MCGP), National Cancer Institute (NCI), NIH, Frederick, Maryland, USA.
  • Morris H; Tumor Angiogenesis Unit, Mouse Cancer Genetics Program (MCGP), National Cancer Institute (NCI), NIH, Frederick, Maryland, USA.
  • Swing DA; Tumor Angiogenesis Unit, Mouse Cancer Genetics Program (MCGP), National Cancer Institute (NCI), NIH, Frederick, Maryland, USA.
  • Haines DC; Tumor Angiogenesis Unit, Mouse Cancer Genetics Program (MCGP), National Cancer Institute (NCI), NIH, Frederick, Maryland, USA.
  • Wang Y; Transgenic Core Facility, MCGP, NCI, Frederick, Maryland, USA.
  • Hwang J; Transgenic Core Facility, MCGP, NCI, Frederick, Maryland, USA.
  • Feng Y; Veterinary Pathology Section, Pathology/Histotechnology Laboratory, Leidos Biomedical Research Inc., FNLCR, Frederick, Maryland, USA.
  • Welsch D; Protein Interactions Section, Cancer and Inflammation Program, NCI, NIH, Frederick, Maryland, USA.
  • DeCrescenzo G; Protein Interactions Section, Cancer and Inflammation Program, NCI, NIH, Frederick, Maryland, USA.
  • Chaudhary A; Tumor Angiogenesis Unit, Mouse Cancer Genetics Program (MCGP), National Cancer Institute (NCI), NIH, Frederick, Maryland, USA.
  • Zudaire E; Protein Interactions Section, Cancer and Inflammation Program, NCI, NIH, Frederick, Maryland, USA.
  • Dimitrov DS; BioMed Valley Discoveries Inc., Kansas City, Missouri, USA.
  • St Croix B; BioMed Valley Discoveries Inc., Kansas City, Missouri, USA.
J Clin Invest ; 128(7): 2927-2943, 2018 07 02.
Article en En | MEDLINE | ID: mdl-29863500
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Receptores de Superficie Celular / Inmunoconjugados / Proteínas de Neoplasias / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Revista: J Clin Invest Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Receptores de Superficie Celular / Inmunoconjugados / Proteínas de Neoplasias / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Revista: J Clin Invest Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos