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The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation.
He, Jun; Gao, Hao-Xue; Yang, Na; Zhu, Xiao-Dong; Sun, Run-Bin; Xie, Yuan; Zeng, Cai-Hong; Zhang, Jing-Wei; Wang, Jian-Kun; Ding, Fei; Aa, Ji-Ye; Wang, Guang-Ji.
Afiliación
  • He J; Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 210009, Nanjing, China.
  • Gao HX; Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 210009, Nanjing, China.
  • Yang N; Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 210009, Nanjing, China.
  • Zhu XD; Research Institute of Nephrology of PLA, Jinling Hospital, 210002, Nanjing, China.
  • Sun RB; Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 210009, Nanjing, China.
  • Xie Y; Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 210009, Nanjing, China.
  • Zeng CH; Research Institute of Nephrology of PLA, Jinling Hospital, 210002, Nanjing, China.
  • Zhang JW; Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 210009, Nanjing, China.
  • Wang JK; Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 210009, Nanjing, China.
  • Ding F; Nanjing Hailing Pharmaceutical Co. Ltd., Yangzi River Pharmaceutical Group, Co. Ltd., 210049, Nanjing, China.
  • Aa JY; Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 210009, Nanjing, China. jiyea@cpu.edu.cn.
  • Wang GJ; Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 210009, Nanjing, China. guangjiwang@hotmail.com.
Acta Pharmacol Sin ; 40(1): 86-97, 2019 Jan.
Article en En | MEDLINE | ID: mdl-29930278
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Rodanina / Aldehído Reductasa / Sustancias Protectoras / Nefropatías Diabéticas / Inhibidores Enzimáticos / Tiazolidinas Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Rodanina / Aldehído Reductasa / Sustancias Protectoras / Nefropatías Diabéticas / Inhibidores Enzimáticos / Tiazolidinas Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China