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Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer.
Viswanathan, Srinivas R; Nogueira, Marina F; Buss, Colin G; Krill-Burger, John M; Wawer, Mathias J; Malolepsza, Edyta; Berger, Ashton C; Choi, Peter S; Shih, Juliann; Taylor, Alison M; Tanenbaum, Benjamin; Pedamallu, Chandra Sekhar; Cherniack, Andrew D; Tamayo, Pablo; Strathdee, Craig A; Lage, Kasper; Carr, Steven A; Schenone, Monica; Bhatia, Sangeeta N; Vazquez, Francisca; Tsherniak, Aviad; Hahn, William C; Meyerson, Matthew.
Afiliación
  • Viswanathan SR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Nogueira MF; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Buss CG; Harvard Medical School, Boston, MA, USA.
  • Krill-Burger JM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wawer MJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Malolepsza E; Harvard-MIT Department of Health Sciences and Technology, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Boston, MA, USA.
  • Berger AC; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Choi PS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Shih J; Chemical Biology and Therapeutics Science Program, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Taylor AM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Tanenbaum B; Department of Surgery, Massachusetts General Hospital, Boston, MA, USA.
  • Pedamallu CS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Cherniack AD; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Tamayo P; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Strathdee CA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Lage K; Harvard Medical School, Boston, MA, USA.
  • Carr SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Schenone M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Bhatia SN; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Vazquez F; Harvard Medical School, Boston, MA, USA.
  • Tsherniak A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Hahn WC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Meyerson M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nat Genet ; 50(7): 937-943, 2018 07.
Article en En | MEDLINE | ID: mdl-29955178

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cromosomas Humanos Par 1 / Neoplasias Límite: Animals / Female / Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cromosomas Humanos Par 1 / Neoplasias Límite: Animals / Female / Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos