Coronary artery calcium and intima-media thickness are associated with level of cytomegalovirus immunoglobulin G in HIV-infected patients.

Knudsen, A; Kristoffersen, U S; Panum, I; Hansen, Y B; Skottrup, P D; Hasbak, P; Kjaer, A; Lebech, A-M

Knudsen, A; Kristoffersen, U S; Panum, I; Hansen, Y B; Skottrup, P D; Hasbak, P; Kjaer, A; Lebech, A-M.

Afiliación

Knudsen A; Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre.
Kristoffersen US; Department of Clinical Physiology, Nuclear Medicine & PET, Copenhagen University Hospital, Rigshospitalet, Copenhagen.
Panum I; Cluster for Molecular Imaging, Department of Biomedical Sciences, University of Copenhagen, Copenhagen.
Hansen YB; Department of Clinical Physiology, Nuclear Medicine & PET, Copenhagen University Hospital, Rigshospitalet, Copenhagen.
Skottrup PD; Cluster for Molecular Imaging, Department of Biomedical Sciences, University of Copenhagen, Copenhagen.
Hasbak P; Department of Clinical Microbiology, Copenhagen University Hospital, Hvidovre.
Kjaer A; Department Clinical Biochemistry, Copenhagen University Hospital, Glostrup.
Lebech AM; Department of Clinical Biochemistry, Copenhagen University Hospital, Hvidovre.

HIV Med ; 20(1): 60-62, 2019 01.

Article en En | MEDLINE | ID: mdl-30182478

ABSTRACT

ABSTRACT

Coinfection with cytomegalovirus (CMV) may be involved in cardiovascular disease in HIV-infected patients. We found that higher level of CMV immunoglobulin G (IgG) was independently associated with an increased risk of coronary artery calcium and higher intima-media thickness in HIV-infected patients but not in healthy controls after adjustment for other cardiovascular risk factors and levels of herpes viridae IgG.

Asunto(s)

Arterias Carótidas/diagnóstico por imagen; Infecciones por Citomegalovirus/inmunología; Citomegalovirus/inmunología; Infecciones por VIH/inmunología; Inmunoglobulinas Intravenosas/metabolismo; Calcio/metabolismo; Grosor Intima-Media Carotídeo; Estudios de Casos y Controles; Coinfección; Estudios Transversales; Femenino; Infecciones por VIH/complicaciones; Humanos; Masculino; Persona de Mediana Edad; Factores de Riesgo

Palabras clave

HIV infection; atherosclerosis; cardiovascular disease; coronary artery calcium; cytomegalovirus

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Arterias Carótidas / Infecciones por VIH / Inmunoglobulinas Intravenosas / Infecciones por Citomegalovirus / Citomegalovirus Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: HIV Med Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2019 Tipo del documento: Article

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