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LKB1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation.
Zulato, E; Ciccarese, F; Agnusdei, V; Pinazza, M; Nardo, G; Iorio, E; Curtarello, M; Silic-Benussi, M; Rossi, E; Venturoli, C; Panieri, E; Santoro, M M; Di Paolo, V; Quintieri, L; Ciminale, V; Indraccolo, S.
Afiliación
  • Zulato E; Istituto Oncologico Veneto IOV - IRCCS, Padova, Italia.
  • Ciccarese F; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
  • Agnusdei V; Istituto Oncologico Veneto IOV - IRCCS, Padova, Italia.
  • Pinazza M; Istituto Oncologico Veneto IOV - IRCCS, Padova, Italia.
  • Nardo G; Istituto Oncologico Veneto IOV - IRCCS, Padova, Italia.
  • Iorio E; Core Facilities Istituto Superiore di Sanità, Roma, Italy.
  • Curtarello M; Istituto Oncologico Veneto IOV - IRCCS, Padova, Italia.
  • Silic-Benussi M; Istituto Oncologico Veneto IOV - IRCCS, Padova, Italia.
  • Rossi E; Istituto Oncologico Veneto IOV - IRCCS, Padova, Italia; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
  • Venturoli C; Istituto Oncologico Veneto IOV - IRCCS, Padova, Italia.
  • Panieri E; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.
  • Santoro MM; Department of Biology, University of Padova, Padova, Italy.
  • Di Paolo V; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
  • Quintieri L; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
  • Ciminale V; Istituto Oncologico Veneto IOV - IRCCS, Padova, Italia; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
  • Indraccolo S; Istituto Oncologico Veneto IOV - IRCCS, Padova, Italia. Electronic address: stefano.indraccolo@unipd.it.
Biochem Pharmacol ; 156: 479-490, 2018 10.
Article en En | MEDLINE | ID: mdl-30222967
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cisplatino / Proteínas Serina-Treonina Quinasas / Estrés Oxidativo / Rayos gamma / Glutatión / Peróxido de Hidrógeno Tipo de estudio: Diagnostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Biochem Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cisplatino / Proteínas Serina-Treonina Quinasas / Estrés Oxidativo / Rayos gamma / Glutatión / Peróxido de Hidrógeno Tipo de estudio: Diagnostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Biochem Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Italia