A multidisciplinary review of triphalangeal thumb.
J Hand Surg Eur Vol
; 44(1): 59-68, 2019 Jan.
Article
en En
| MEDLINE
| ID: mdl-30318985
ABSTRACT
Despite being a rare congenital limb anomaly, triphalangeal thumb is a subject of research in various scientific fields, providing new insights in clinical research and evolutionary biology. The findings of triphalangeal thumb can be predictive for other congenital anomalies as part of an underlying syndrome. Furthermore, triphalangeal thumb is still being used as a model in molecular genetics to study gene regulation by long-range regulatory elements. We present a review that summarizes a number of scientifically relevant topics that involve the triphalangeal thumb phenotype. Future initiatives involving multidisciplinary teams collaborating in the field of triphalangeal thumb research can lead to a better understanding of the pathogenesis and molecular mechanisms of this condition as well as other congenital upper limb anomalies.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Pulgar
/
Deformidades Congénitas de la Mano
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
J Hand Surg Eur Vol
Año:
2019
Tipo del documento:
Article
País de afiliación:
Países Bajos