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Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors.
Gao, Cheng-Zhi; Dong, Wei; Cui, Zhi-Wen; Yuan, Qiong; Hu, Xia-Min; Wu, Qing-Ming; Han, Xianlin; Xu, Yao; Min, Zhen-Li.
Afiliación
  • Gao CZ; a Hubei Province Key Laboratory of Occupational Hazard Identification and Control , Wuhan University of Science and Technology , Wuhan , China.
  • Dong W; a Hubei Province Key Laboratory of Occupational Hazard Identification and Control , Wuhan University of Science and Technology , Wuhan , China.
  • Cui ZW; a Hubei Province Key Laboratory of Occupational Hazard Identification and Control , Wuhan University of Science and Technology , Wuhan , China.
  • Yuan Q; a Hubei Province Key Laboratory of Occupational Hazard Identification and Control , Wuhan University of Science and Technology , Wuhan , China.
  • Hu XM; b College of Pharmacy , Shanghai University of Medicine & Health Sciences , Shanghai , China.
  • Wu QM; a Hubei Province Key Laboratory of Occupational Hazard Identification and Control , Wuhan University of Science and Technology , Wuhan , China.
  • Han X; c Barshop Institute for Longevity and Aging Studies , University of Texas Health Science Center at San Antonio , San Antonio , TX , USA.
  • Xu Y; d College of Life Science and Health , Wuhan University of Science and Technology , Wuhan , China.
  • Min ZL; a Hubei Province Key Laboratory of Occupational Hazard Identification and Control , Wuhan University of Science and Technology , Wuhan , China.
J Enzyme Inhib Med Chem ; 34(1): 150-162, 2019 Dec.
Article en En | MEDLINE | ID: mdl-30427217
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ftalazinas / Piperazinas / Acetilcolinesterasa / Inhibidores de la Colinesterasa / Simulación del Acoplamiento Molecular / Poli(ADP-Ribosa) Polimerasa-1 / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ftalazinas / Piperazinas / Acetilcolinesterasa / Inhibidores de la Colinesterasa / Simulación del Acoplamiento Molecular / Poli(ADP-Ribosa) Polimerasa-1 / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: China