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Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression.
Liu, Na; Luo, Jing; Kuang, Dong; Xu, Sanpeng; Duan, Yaqi; Xia, Yu; Wei, Zhengping; Xie, Xiuxiu; Yin, Bingjiao; Chen, Fang; Luo, Shunqun; Liu, Huicheng; Wang, Jing; Jiang, Kan; Gong, Feili; Tang, Zhao-Hui; Cheng, Xiang; Li, Huabin; Li, Zhuoya; Laurence, Arian; Wang, Guoping; Yang, Xiang-Ping.
Afiliación
  • Liu N; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
  • Luo J; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
  • Kuang D; Institute of Pathology, Tongji Hospital, HUST, Wuhan, China.
  • Xu S; Department of Pathology, School of Basic Medicine, and.
  • Duan Y; Institute of Pathology, Tongji Hospital, HUST, Wuhan, China.
  • Xia Y; Department of Pathology, School of Basic Medicine, and.
  • Wei Z; Institute of Pathology, Tongji Hospital, HUST, Wuhan, China.
  • Xie X; Department of Pathology, School of Basic Medicine, and.
  • Yin B; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
  • Chen F; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
  • Luo S; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
  • Liu H; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
  • Wang J; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
  • Jiang K; The Center for Biomedical Research, Tongji Hospital, Tongji Medical College, HUST, Wuhan, China.
  • Gong F; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
  • Tang ZH; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
  • Cheng X; Biodata Mining and Discovery Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland, USA.
  • Li H; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
  • Li Z; Department of Surgery, Tongji Hospital, HUST, Wuhan, China.
  • Laurence A; Laboratory of Cardiovascular Immunology, Institute of Cardiology, Union Hospital, Tongji Medical College, HUST, Wuhan, China.
  • Wang G; Department of Otolaryngology, Head and Neck Surgery, Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China.
  • Yang XP; Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China.
J Clin Invest ; 129(2): 631-646, 2019 02 01.
Article en En | MEDLINE | ID: mdl-30431439

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Regulación Enzimológica de la Expresión Génica / Regulación Neoplásica de la Expresión Génica / Ácido Láctico / ATPasas de Translocación de Protón Vacuolares / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Microambiente Tumoral / Adenocarcinoma del Pulmón / Neoplasias Pulmonares / Macrófagos / Proteínas de Neoplasias Tipo de estudio: Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: J Clin Invest Año: 2019 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Regulación Enzimológica de la Expresión Génica / Regulación Neoplásica de la Expresión Génica / Ácido Láctico / ATPasas de Translocación de Protón Vacuolares / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Microambiente Tumoral / Adenocarcinoma del Pulmón / Neoplasias Pulmonares / Macrófagos / Proteínas de Neoplasias Tipo de estudio: Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: J Clin Invest Año: 2019 Tipo del documento: Article País de afiliación: China