Lymphotoxin-ß receptor-NIK signaling induces alternative RELB/NF-&#954;B2 activation to promote metastatic gene expression and cell migration in head and neck cancer.

Das, Rita; Coupar, Jamie; Clavijo, Paul E; Saleh, Anthony; Cheng, Tsu-Fan; Yang, Xinping; Chen, Jianhong; Van Waes, Carter; Chen, Zhong

Lymphotoxin-ß receptor-NIK signaling induces alternative RELB/NF-κB2 activation to promote metastatic gene expression and cell migration in head and neck cancer.

Das, Rita; Coupar, Jamie; Clavijo, Paul E; Saleh, Anthony; Cheng, Tsu-Fan; Yang, Xinping; Chen, Jianhong; Van Waes, Carter; Chen, Zhong.

Afiliación

Das R; Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.
Coupar J; Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.
Clavijo PE; Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.
Saleh A; Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.
Cheng TF; Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.
Yang X; Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.
Chen J; Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.
Van Waes C; Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.
Chen Z; Tumor Biology Section, Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland.

Mol Carcinog ; 58(3): 411-425, 2019 03.

Article en En | MEDLINE | ID: mdl-30488488

Asunto(s)

Carcinoma de Células Escamosas/secundario; Neoplasias de Cabeza y Cuello/patología; Receptor beta de Linfotoxina/metabolismo; Linfotoxina-alfa/metabolismo; Linfotoxina beta/metabolismo; Proteínas Serina-Treonina Quinasas/metabolismo; Factor de Transcripción ReIB/metabolismo; Biomarcadores de Tumor/genética; Biomarcadores de Tumor/metabolismo; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/metabolismo; Movimiento Celular; Proliferación Celular; Regulación Neoplásica de la Expresión Génica; Neoplasias de Cabeza y Cuello/genética; Neoplasias de Cabeza y Cuello/metabolismo; Humanos; Receptor beta de Linfotoxina/genética; Linfotoxina-alfa/genética; Linfotoxina beta/genética; Pronóstico; Proteínas Serina-Treonina Quinasas/genética; Transducción de Señal; Factor de Transcripción ReIB/genética; Células Tumorales Cultivadas; Quinasa de Factor Nuclear kappa B

Palabras clave

HNSCC; LTß/LTß receptor; NIK; RELB/NF-κB2; migration

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Linfotoxina-alfa / Proteínas Serina-Treonina Quinasas / Factor de Transcripción ReIB / Linfotoxina beta / Receptor beta de Linfotoxina / Neoplasias de Cabeza y Cuello Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Carcinog Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2019 Tipo del documento: Article

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