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The membrane tethered matrix metalloproteinase MT1-MMP triggers an outside-in DNA damage response that impacts chemo- and radiotherapy responses of breast cancer.
Thakur, Varsha; Zhang, Keman; Savadelis, Alyssa; Zmina, Patrick; Aguila, Brittany; Welford, Scott M; Abdul-Karim, Fadi; Bonk, Kristen W; Keri, Ruth A; Bedogni, Barbara.
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  • Thakur V; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA; Department of Dermatology, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
  • Zhang K; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Savadelis A; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Zmina P; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA; Department of Dermatology, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
  • Aguila B; Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
  • Welford SM; Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
  • Abdul-Karim F; Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH, 44119, USA.
  • Bonk KW; Department of Pharmacology, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Keri RA; Department of Pharmacology, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Bedogni B; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA; Department of Dermatology, University of Miami Miller School of Medicine, Miami, FL, 33136, USA. Electronic address: bxb602@miami.edu.
Cancer Lett ; 443: 115-124, 2019 02 28.
Article en En | MEDLINE | ID: mdl-30502358
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tolerancia a Radiación / Neoplasias de la Mama / Resistencia a Antineoplásicos / Metaloproteinasa 14 de la Matriz Límite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tolerancia a Radiación / Neoplasias de la Mama / Resistencia a Antineoplásicos / Metaloproteinasa 14 de la Matriz Límite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos