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Myricetin inhibits NLRP3 inflammasome activation via reduction of ROS-dependent ubiquitination of ASC and promotion of ROS-independent NLRP3 ubiquitination.
Chen, Hanwen; Lin, Hui; Xie, Shujun; Huang, Bo; Qian, Yufeng; Chen, Kelie; Niu, Yuequn; Shen, Han-Ming; Cai, Jianting; Li, Peiwei; Leng, Jianhang; Yang, Hao; Xia, Dajing; Wu, Yihua.
Afiliación
  • Chen H; Department of Toxicology, School of Public Health, Zhejiang University, Zhejiang, Hangzhou 310058, China; Department of Gastroenterology, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, Hangzhou 310009, China.
  • Lin H; Department of Toxicology, School of Public Health, Zhejiang University, Zhejiang, Hangzhou 310058, China; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Zhejiang, Hangzhou 310006, China.
  • Xie S; Department of Toxicology, School of Public Health, Zhejiang University, Zhejiang, Hangzhou 310058, China.
  • Huang B; Department of Toxicology, School of Public Health, Zhejiang University, Zhejiang, Hangzhou 310058, China.
  • Qian Y; Department of Cardiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Zhejiang, Hangzhou 310006, China.
  • Chen K; Department of Toxicology, School of Public Health, Zhejiang University, Zhejiang, Hangzhou 310058, China; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Zhejiang, Hangzhou 310006, China.
  • Niu Y; Department of Toxicology, School of Public Health, Zhejiang University, Zhejiang, Hangzhou 310058, China.
  • Shen HM; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, 119077, Singapore.
  • Cai J; Department of Gastroenterology, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, Hangzhou 310009, China.
  • Li P; Department of Gastroenterology, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, Hangzhou 310009, China.
  • Leng J; Central Laboratory, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Zhejiang, Hangzhou 310006, China.
  • Yang H; Department of Toxicology, School of Public Health, Zhejiang University, Zhejiang, Hangzhou 310058, China.
  • Xia D; Department of Toxicology, School of Public Health, Women's Hospital, School of Medicine, Zhejiang University, Zhejiang, Hangzhou 310058, China. Electronic address: dxia@zju.edu.cn.
  • Wu Y; Department of Toxicology, School of Public Health, Zhejiang University, Zhejiang, Hangzhou 310058, China. Electronic address: georgewu@zju.edu.cn.
Toxicol Appl Pharmacol ; 365: 19-29, 2019 02 15.
Article en En | MEDLINE | ID: mdl-30594691
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Peritonitis / Flavonoides / Especies Reactivas de Oxígeno / Macrófagos Peritoneales / Sepsis / Proteínas Adaptadoras de Señalización CARD / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR / Antiinflamatorios Límite: Animals / Humans / Male Idioma: En Revista: Toxicol Appl Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Peritonitis / Flavonoides / Especies Reactivas de Oxígeno / Macrófagos Peritoneales / Sepsis / Proteínas Adaptadoras de Señalización CARD / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR / Antiinflamatorios Límite: Animals / Humans / Male Idioma: En Revista: Toxicol Appl Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China