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Tenacigenin B ester derivatives from Marsdenia tenacissima actively inhibited CYP3A4 and enhanced in vivo antitumor activity of paclitaxel.
Xie, Bin; Lu, Yuan-Yuan; Luo, Zhuo-Hui; Qu, Zhao; Zheng, Chun-Ge; Huang, Xin-An; Zhou, Hong-Yan; Hu, Ying-Jie; Shen, Xiao-Ling.
Afiliación
  • Xie B; Laboratory of Chinese Herbal Drug Discovery, Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, PR China.
  • Lu YY; Laboratory of Chinese Herbal Drug Discovery, Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, PR China. Electronic address: luyuanyuan@gzucm.edu.cn.
  • Luo ZH; Laboratory of Chinese Herbal Drug Discovery, Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, PR China.
  • Qu Z; Laboratory of Chinese Herbal Drug Discovery, Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, PR China.
  • Zheng CG; Laboratory of Chinese Herbal Drug Discovery, Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, PR China.
  • Huang XA; Laboratory of Chinese Herbal Drug Discovery, Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, PR China. Electronic address: xinanhuang@gzucm.edu.cn.
  • Zhou HY; Laboratory of Chinese Herbal Drug Discovery, Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, PR China. Electronic address: zhouhy@gzucm.edu.cn.
  • Hu YJ; Laboratory of Chinese Herbal Drug Discovery, Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, PR China. Electronic address: yingjiehu@gzucm.edu.cn.
  • Shen XL; Laboratory of Chinese Herbal Drug Discovery, Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405 Guangdong, PR China. Electronic address: xshen2@gzucm.edu.cn.
J Ethnopharmacol ; 235: 309-319, 2019 May 10.
Article en En | MEDLINE | ID: mdl-30772481
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Esteroides / Paclitaxel / Marsdenia / Antineoplásicos Fitogénicos Límite: Animals / Female / Humans Idioma: En Revista: J Ethnopharmacol Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Esteroides / Paclitaxel / Marsdenia / Antineoplásicos Fitogénicos Límite: Animals / Female / Humans Idioma: En Revista: J Ethnopharmacol Año: 2019 Tipo del documento: Article