Role of Ancillary Techniques in Gynecologic Cytopathology Specimens.
Acta Cytol
; 64(1-2): 63-70, 2020.
Article
en En
| MEDLINE
| ID: mdl-30889579
ABSTRACT
The association between high-risk genotypes of human papillomavirus (hr-HPV) and cervical cancer is well established. As hr-HPV testing is rapidly becoming a part of routine cervical cancer screening, either in conjunction with cytology or as primary testing, the management of hr-HPV-positive women has to be tailored in a way that increases the detection of cervical abnormalities while decreasing unnecessary colposcopic biopsies or other invasive procedures. In this review, we discuss the overall utility and strategies of hr-HPV testing, as well as the advantages and limitations of potential triage strategies for hr-HPV-positive women, including HPV genotyping, p16/Ki-67 dual staining, and methylation assays.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Papillomaviridae
/
Neoplasias del Cuello Uterino
/
Citodiagnóstico
/
Infecciones por Papillomavirus
Tipo de estudio:
Diagnostic_studies
/
Screening_studies
Límite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Acta Cytol
Año:
2020
Tipo del documento:
Article
País de afiliación:
Estados Unidos