ACE2 inhibits breast cancer angiogenesis via suppressing the VEGFa/VEGFR2/ERK pathway.

Zhang, Qi; Lu, Sihong; Li, Tianfu; Yu, Liang; Zhang, Yunjian; Zeng, Huijuan; Qian, Xueke; Bi, Jiong; Lin, Ying

Zhang, Qi; Lu, Sihong; Li, Tianfu; Yu, Liang; Zhang, Yunjian; Zeng, Huijuan; Qian, Xueke; Bi, Jiong; Lin, Ying.

Afiliación

Zhang Q; Breast Disease Center, The First Affiliated Hospital, Sun Yat-Sen University, No.58 of Zhongshan 2nd road, Yuexiu district, Guangzhou, 510080, China.
Lu S; Guangdong Key Engineering Laboratory for Diagnosis and Treatment of Vascular Disease, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.
Li T; Breast Disease Center, The First Affiliated Hospital, Sun Yat-Sen University, No.58 of Zhongshan 2nd road, Yuexiu district, Guangzhou, 510080, China.
Yu L; Laboratory of Surgery, The First Affiliated Hospital, Sun Yat-Sen University, No. 58 of Zhongshan 2nd road, Yuexiu district, Guangzhou, 510080, China.
Zhang Y; Breast Disease Center, The First Affiliated Hospital, Sun Yat-Sen University, No.58 of Zhongshan 2nd road, Yuexiu district, Guangzhou, 510080, China.
Zeng H; Breast Disease Center, The First Affiliated Hospital, Sun Yat-Sen University, No.58 of Zhongshan 2nd road, Yuexiu district, Guangzhou, 510080, China.
Qian X; Breast Disease Center, The First Affiliated Hospital, Sun Yat-Sen University, No.58 of Zhongshan 2nd road, Yuexiu district, Guangzhou, 510080, China.
Bi J; Breast Disease Center, The First Affiliated Hospital, Sun Yat-Sen University, No.58 of Zhongshan 2nd road, Yuexiu district, Guangzhou, 510080, China.
Lin Y; The First Affiliated Hospital, Zhengzhou University, Zhengzhou, 450000, China.

J Exp Clin Cancer Res ; 38(1): 173, 2019 Apr 25.

Article en En | MEDLINE | ID: mdl-31023337

Asunto(s)

Neoplasias de la Mama/genética; Neovascularización Patológica/genética; Peptidil-Dipeptidasa A/genética; Factor A de Crecimiento Endotelial Vascular/genética; Receptor 2 de Factores de Crecimiento Endotelial Vascular/genética; Enzima Convertidora de Angiotensina 2; Animales; Mama/metabolismo; Mama/patología; Neoplasias de la Mama/patología; Movimiento Celular/genética; Proliferación Celular/genética; Modelos Animales de Enfermedad; Femenino; Regulación Neoplásica de la Expresión Génica/genética; Células Endoteliales de la Vena Umbilical Humana; Humanos; Sistema de Señalización de MAP Quinasas/genética; Células MCF-7; Metástasis de la Neoplasia; Recurrencia Local de Neoplasia/genética; Recurrencia Local de Neoplasia/patología; Fosforilación; Pez Cebra

Palabras clave

ACE2; Angiogenesis; Breast cancer; ERK; VEGFR2; VEGFa

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Peptidil-Dipeptidasa A / Receptor 2 de Factores de Crecimiento Endotelial Vascular / Factor A de Crecimiento Endotelial Vascular / Neovascularización Patológica Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: J Exp Clin Cancer Res Año: 2019 Tipo del documento: Article País de afiliación: China

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