RB constrains lineage fidelity and multiple stages of tumour progression and metastasis.

Walter, David M; Yates, Travis J; Ruiz-Torres, Miguel; Kim-Kiselak, Caroline; Gudiel, A Andrea; Deshpande, Charuhas; Wang, Walter Z; Cicchini, Michelle; Stokes, Kate L; Tobias, John W; Buza, Elizabeth; Feldser, David M

Walter, David M; Yates, Travis J; Ruiz-Torres, Miguel; Kim-Kiselak, Caroline; Gudiel, A Andrea; Deshpande, Charuhas; Wang, Walter Z; Cicchini, Michelle; Stokes, Kate L; Tobias, John W; Buza, Elizabeth; Feldser, David M.

Afiliación

Walter DM; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Yates TJ; Cell and Molecular Biology Graduate Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Ruiz-Torres M; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kim-Kiselak C; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Gudiel AA; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Deshpande C; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Wang WZ; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Cicchini M; Abramson Cancer Center, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Stokes KL; Vagelos Scholars Program, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA.
Tobias JW; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Buza E; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Feldser DM; Abramson Cancer Center, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.

Nature ; 569(7756): 423-427, 2019 05.

Article en En | MEDLINE | ID: mdl-31043741

Asunto(s)

Linaje de la Célula; Progresión de la Enfermedad; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patología; Metástasis de la Neoplasia; Retinoblastoma/metabolismo; Células 3T3; Adenocarcinoma/metabolismo; Adenocarcinoma/patología; Animales; Linaje de la Célula/genética; Quinasa 2 Dependiente de la Ciclina/deficiencia; Quinasa 2 Dependiente de la Ciclina/genética; Quinasa 2 Dependiente de la Ciclina/metabolismo; Quinasa 4 Dependiente de la Ciclina/antagonistas & inhibidores; Quinasa 6 Dependiente de la Ciclina/antagonistas & inhibidores; Células HEK293; Humanos; Neoplasias Pulmonares/genética; Sistema de Señalización de MAP Quinasas; Masculino; Ratones; Metástasis de la Neoplasia/genética; Retinoblastoma/genética

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Retinoblastoma / Progresión de la Enfermedad / Linaje de la Célula / Neoplasias Pulmonares / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Nature Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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