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PI3Kα inhibitors sensitize esophageal squamous cell carcinoma to radiation by abrogating survival signals in tumor cells and tumor microenvironment.
Shi, Jia-Jie; Xing, Hui; Wang, Yu-Xiang; Zhang, Xi; Zhan, Qi-Min; Geng, Mei-Yu; Ding, Jian; Meng, Ling-Hua.
Afiliación
  • Shi JJ; Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Xing H; Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Wang YX; Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Zhang X; Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China.
  • Zhan QM; State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
  • Geng MY; University of Chinese Academy of Sciences, Beijing, 100049, China; Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China.
  • Ding J; University of Chinese Academy of Sciences, Beijing, 100049, China; Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China. Electronic address: jding@simm.ac.cn.
  • Meng LH; Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: lhmeng@simm.ac.cn.
Cancer Lett ; 459: 145-155, 2019 09 10.
Article en En | MEDLINE | ID: mdl-31173854
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piperazinas / Pirroles / Fármacos Sensibilizantes a Radiaciones / Neoplasias Esofágicas / Morfolinas / Fosfatidilinositol 3-Quinasa Clase I / Carcinoma de Células Escamosas de Esófago Tipo de estudio: Clinical_trials Límite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piperazinas / Pirroles / Fármacos Sensibilizantes a Radiaciones / Neoplasias Esofágicas / Morfolinas / Fosfatidilinositol 3-Quinasa Clase I / Carcinoma de Células Escamosas de Esófago Tipo de estudio: Clinical_trials Límite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Año: 2019 Tipo del documento: Article País de afiliación: China