HPV infections and flat penile lesions of the penis in men who have sex with men.
Papillomavirus Res
; 8: 100173, 2019 12.
Article
en En
| MEDLINE
| ID: mdl-31226447
ABSTRACT
BACKGROUND:
Flat penile lesions (FPL) in heterosexual men are thought to play a role in the transmission of HPV. We investigated the association between FPL and penile HPV, and explored determinants of FPL in men who have sex with men (MSM).METHODS:
In 2015-2016, MSM were recruited based on HIV and penile HPV status in a previous cohort. MSM self-completed a questionnaire. Peniscopy was performed after application of acetic acid to visualize FPL. Penile physician-collected samples were tested for HPV-DNA using the highly sensitive SPF10-PCR DEIA/LiPA25 system. HPV viral load (VL) was determined using a quantitative type-specific (q)PCR targeting the L1-region. Presence of HPV and HIV, HPV VL and circumcision status were compared between MSM with and without FPL.RESULTS:
We included 116 MSM, of whom 59/116 (51%) MSM were HIV-positive and 54/116 (47%) had FPL. A penile HPV infection was present in 31/54 (57%) MSM with FPL and 34/62 (55%) MSM without FPL (pâ¯=â¯0.8). There was no difference between MSM with and without FPL regarding presence of penile HPV infection, HPV VL, HIV status or circumcision status (pâ¯>â¯0.05 for all).CONCLUSION:
Among MSM in Amsterdam, we found no association between FPL and penile HPV, HPV VL, HIV status or circumcision status.Palabras clave
Texto completo:
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Base de datos:
MEDLINE
Asunto principal:
Papillomaviridae
/
Enfermedades del Pene
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Pene
/
Homosexualidad Masculina
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Infecciones por Papillomavirus
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Papillomavirus Res
Año:
2019
Tipo del documento:
Article