Taxifolin inhibits breast cancer cells proliferation, migration and invasion by promoting mesenchymal to epithelial transition via ß-catenin signaling.

Li, Jie; Hu, Lu; Zhou, Tao; Gong, Xia; Jiang, Rong; Li, Hongzhong; Kuang, Ge; Wan, Jingyuan; Li, Hongyuan

Li, Jie; Hu, Lu; Zhou, Tao; Gong, Xia; Jiang, Rong; Li, Hongzhong; Kuang, Ge; Wan, Jingyuan; Li, Hongyuan.

Afiliación

Li J; Department of Endocrine and Breast Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Hu L; Department of Pharmacology, Chongqing Medical University, Chongqing 400016, China.
Zhou T; Department of Pharmacology, Chongqing Medical University, Chongqing 400016, China.
Gong X; Department of Anatomy, Chongqing Medical University, Chongqing 400016, China.
Jiang R; Laboratory of Stem Cell and Tissue Engineering, Chongqing Medical University, Chongqing 400016, China.
Li H; Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Kuang G; Department of Pharmacology, Chongqing Medical University, Chongqing 400016, China. Electronic address: kuangge72@aliyun.com.
Wan J; Department of Pharmacology, Chongqing Medical University, Chongqing 400016, China. Electronic address: jywan@cqmu.edu.cn.
Li H; Department of Endocrine and Breast Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. Electronic address: hongy_li@hotmail.com.

Life Sci ; 232: 116617, 2019 Sep 01.

Article en En | MEDLINE | ID: mdl-31260685

Asunto(s)

Neoplasias de la Mama/tratamiento farmacológico; Quercetina/análogos & derivados; Animales; Neoplasias de la Mama/metabolismo; Neoplasias de la Mama/patología; Línea Celular Tumoral; Movimiento Celular/efectos de los fármacos; Proliferación Celular/efectos de los fármacos; Transición Epitelial-Mesenquimal/efectos de los fármacos; Femenino; Humanos; Células MCF-7; Ratones; Ratones Endogámicos BALB C; Invasividad Neoplásica; Quercetina/farmacología; Transducción de Señal/efectos de los fármacos; Ensayos Antitumor por Modelo de Xenoinjerto; beta Catenina/metabolismo

Palabras clave

Breast cancer; Epithelial-to-mesenchymal transition; Metastasis; Taxifolin; ß-Catenin

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Quercetina / Neoplasias de la Mama Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Life Sci Año: 2019 Tipo del documento: Article País de afiliación: China

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