Sarcomatoid Variant of Primary Cutaneous Anaplastic Large Cell Lymphoma.
Am J Dermatopathol
; 41(12): e164-e167, 2019 Dec.
Article
en En
| MEDLINE
| ID: mdl-31268929
ABSTRACT
Sarcomatoid variant of primary cutaneous anaplastic large cell lymphoma is rare and is a diagnostic challenge. Clinical manifestation often mimics that of an infectious disease. Predominance of spindle cells in the biopsy specimen prevents from suspecting lymphoma. Here, we report the fourth case of this entity with good prognosis. A 30-year-old woman presented with several nodules on the whole body. The biopsy revealed infiltration of spindle cells in the dermis with myxomatous background. The spindle cells were positive for CD4 and CD30 and negative for CD3, CD8, CD20, and anaplastic lymphoma kinase. Although most of the skin lesions spontaneously resolved, a new red nodule progressively expanded on the left axilla. Finally, the patient received chemotherapy, which resulted in complete remission. The patient is free of disease for 18 months.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Sarcoma
/
Neoplasias Cutáneas
/
Linfoma Anaplásico Cutáneo Primario de Células Grandes
Tipo de estudio:
Prognostic_studies
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Am J Dermatopathol
Año:
2019
Tipo del documento:
Article
País de afiliación:
Japón