Human Replay Spontaneously Reorganizes Experience.
Cell
; 178(3): 640-652.e14, 2019 07 25.
Article
en En
| MEDLINE
| ID: mdl-31280961
ABSTRACT
Knowledge abstracted from previous experiences can be transferred to aid new learning. Here, we asked whether such abstract knowledge immediately guides the replay of new experiences. We first trained participants on a rule defining an ordering of objects and then presented a novel set of objects in a scrambled order. Across two studies, we observed that representations of these novel objects were reactivated during a subsequent rest. As in rodents, human "replay" events occurred in sequences accelerated in time, compared to actual experience, and reversed their direction after a reward. Notably, replay did not simply recapitulate visual experience, but followed instead a sequence implied by learned abstract knowledge. Furthermore, each replay contained more than sensory representations of the relevant objects. A sensory code of object representations was preceded 50 ms by a code factorized into sequence position and sequence identity. We argue that this factorized representation facilitates the generalization of a previously learned structure to new objects.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Aprendizaje
/
Memoria
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Cell
Año:
2019
Tipo del documento:
Article