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Genotype-phenotype association analysis identifies the role of α globin genes in modulating disease severity of ß thalassaemia intermedia in Sri Lanka.
Perera, Shiromi; Allen, Angela; Silva, Ishari; Hapugoda, Menaka; Wickramarathne, M Nirmali; Wijesiriwardena, Indira; Allen, Stephen; Rees, David; Efremov, Dimitar G; Fisher, Christopher A; Weatherall, David J; Premawardhena, Anuja.
Afiliación
  • Perera S; Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka. shiromip@kln.ac.lk.
  • Allen A; MRC Molecular Hematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Silva I; Centre for Tropical and Infectious Disease, Liverpool School of Tropical Medicine, Liverpool, UK.
  • Hapugoda M; Hemal's Thalassemia Care Unit, North Colombo Teaching Hospital, Ragama, Sri Lanka.
  • Wickramarathne MN; Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
  • Wijesiriwardena I; Faculty of Applied Sciences, Sabaragamuwa University of Sri Lanka, Belihulova, Sri Lanka.
  • Allen S; Faculty of Medicine, University of Sri Jayewardhanepura, Nugegoda, Sri Lanka.
  • Rees D; Centre for Tropical and Infectious Disease, Liverpool School of Tropical Medicine, Liverpool, UK.
  • Efremov DG; Department of Paediatric Haematology, King's College Hospital, London, UK.
  • Fisher CA; Molecular Hematology Unit, International Centre for Genetic Engineering and Biotechnology, Rome, Italy.
  • Weatherall DJ; MRC Molecular Hematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Premawardhena A; MRC Molecular Hematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Sci Rep ; 9(1): 10116, 2019 07 12.
Article en En | MEDLINE | ID: mdl-31300739

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Talasemia beta / Globinas alfa Tipo de estudio: Guideline / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article País de afiliación: Sri Lanka

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Talasemia beta / Globinas alfa Tipo de estudio: Guideline / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Sci Rep Año: 2019 Tipo del documento: Article País de afiliación: Sri Lanka