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Influence of model-predicted rivaroxaban exposure and patient characteristics on efficacy and safety outcomes in patients with acute coronary syndrome.
Zhang, Liping; Yan, Xiaoyu; Nandy, Partha; Willmann, Stefan; Fox, Keith A A; Berkowitz, Scott D; Sharma, Amarnath; Hermanowski-Vosatka, Anne; Schmidt, Stephan; Weitz, Jeffrey I; Garmann, Dirk; Peters, Gary.
Afiliación
  • Zhang L; Global Clinical Pharmacology, Janssen Research and Development, LLC, 5 Pauma Valley Ct, Raritan, NJ 08558, USA.
  • Yan X; Janssen Research & Development, LLC, Raritan, NJ, USA.
  • Nandy P; Janssen Research & Development, LLC, Raritan, NJ, USA.
  • Willmann S; Bayer AG, Wuppertal, Germany.
  • Fox KAA; Centre for Cardiovascular Sciences, The University of Edinburgh, Edinburgh, UK.
  • Berkowitz SD; Bayer US LLC, Whippany, NJ, USA.
  • Sharma A; Janssen Research & Development, LLC, Raritan, NJ, USA.
  • Hermanowski-Vosatka A; Janssen Research & Development, LLC, Raritan, NJ, USA.
  • Schmidt S; Department of Pharmaceutics, University of Florida, Orlando, FL, USA.
  • Weitz JI; McMaster University and the Thrombosis & Atherosclerosis Research Institute, Hamilton, ON, Canada.
  • Garmann D; Bayer AG, Wuppertal, Germany.
  • Peters G; Janssen Research & Development, LLC, Raritan, NJ, USA.
Ther Adv Cardiovasc Dis ; 13: 1753944719863641, 2019.
Article en En | MEDLINE | ID: mdl-31364490
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Síndrome Coronario Agudo / Inhibidores del Factor Xa / Rivaroxabán / Modelos Biológicos Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ther Adv Cardiovasc Dis Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / TERAPEUTICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Síndrome Coronario Agudo / Inhibidores del Factor Xa / Rivaroxabán / Modelos Biológicos Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ther Adv Cardiovasc Dis Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / TERAPEUTICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos