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Replicated evidence that endophenotypic expression of schizophrenia polygenic risk is greater in healthy siblings of patients compared to controls, suggesting gene-environment interaction. The EUGEI study.
van Os, Jim; Pries, Lotta-Katrin; Delespaul, Philippe; Kenis, Gunter; Luykx, Jurjen J; Lin, Bochao D; Richards, Alexander L; Akdede, Berna; Binbay, Tolga; Altinyazar, Vesile; Yalinçetin, Berna; Gümüs-Akay, Güvem; Cihan, Burçin; Soygür, Haldun; Ulas, Halis; Cankurtaran, Eylem Sahin; Kaymak, Semra Ulusoy; Mihaljevic, Marina M; Petrovic, Sanja Andric; Mirjanic, Tijana; Bernardo, Miguel; Cabrera, Bibiana; Bobes, Julio; Saiz, Pilar A; García-Portilla, María Paz; Sanjuan, Julio; Aguilar, Eduardo J; Santos, José Luis; Jiménez-López, Estela; Arrojo, Manuel; Carracedo, Angel; López, Gonzalo; González-Peñas, Javier; Parellada, Mara; Maric, Nadja P; Atbasoglu, Cem; Ucok, Alp; Alptekin, Köksal; Saka, Meram Can; Arango, Celso; O'Donovan, Michael; Rutten, Bart P F; Guloksuz, Sinan.
Afiliación
  • van Os J; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Pries LK; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Delespaul P; Department of Psychosis Studies, Institute of Psychiatry, King's College London, King's Health Partners, London, UK.
  • Kenis G; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Luykx JJ; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Lin BD; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Richards AL; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Akdede B; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Binbay T; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Altinyazar V; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, UK.
  • Yalinçetin B; Department of Psychiatry, Dokuz Eylul University School of Medicine, Izmir, Turkey.
  • Gümüs-Akay G; Department of Psychiatry, Dokuz Eylul University School of Medicine, Izmir, Turkey.
  • Cihan B; Department of Psychiatry, Faculty of Medicine, Adnan Menderes University, Aydin, Turkey.
  • Soygür H; Department of Neuroscience, Health Sciences Institute, Dokuz Eylul University, Izmir, Turkey.
  • Ulas H; Ankara University Brain Research Center, Ankara, Turkey.
  • Cankurtaran ES; Department of Psychology, Middle East Technical University, Çankaya, Ankara, Turkey.
  • Kaymak SU; Department of Psychiatry, School of Medicine, Dokuz Eylül University (discharged by decree 701 on July 8, 2018 because of signing "Peace Petition").
  • Mihaljevic MM; Department of Psychiatry, School of Medicine, Dokuz Eylül University (discharged by decree 701 on July 8, 2018 because of signing "Peace Petition").
  • Petrovic SA; Güven Çayyolu Healthcare Campus, Ankara, Turkey.
  • Mirjanic T; Atatürk Research and Training Hospital Psychiatry Clinic, Ankara, Turkey.
  • Bernardo M; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
  • Cabrera B; Clinic for Psychiatry CCS, Belgrade, Serbia.
  • Bobes J; Clinic for Psychiatry CCS, Belgrade, Serbia.
  • Saiz PA; Special Hospital for Psychiatric Disorders Kovin, Kovin, Serbia.
  • García-Portilla MP; Barcelona Clinic Schizophrenia Unit, Neuroscience Institute, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.
  • Sanjuan J; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  • Aguilar EJ; Biomedical Research Networking Centre in Mental Health (CIBERSAM), Madrid, Spain.
  • Santos JL; Barcelona Clinic Schizophrenia Unit, Neuroscience Institute, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.
  • Jiménez-López E; Biomedical Research Networking Centre in Mental Health (CIBERSAM), Madrid, Spain.
  • Arrojo M; Biomedical Research Networking Centre in Mental Health (CIBERSAM), Madrid, Spain.
  • Carracedo A; Department of Psychiatry, School of Medicine, University of Oviedo, Oviedo, Spain.
  • López G; Instituto de Investigación Sanitaria del Principado de Asturias, ISPA, Oviedo, Spain.
  • González-Peñas J; Mental Health Services of Principado de Asturias, SESPA, Oviedo, Spain.
  • Parellada M; Biomedical Research Networking Centre in Mental Health (CIBERSAM), Madrid, Spain.
  • Maric NP; Department of Psychiatry, School of Medicine, University of Oviedo, Oviedo, Spain.
  • Atbasoglu C; Instituto de Investigación Sanitaria del Principado de Asturias, ISPA, Oviedo, Spain.
  • Ucok A; Mental Health Services of Principado de Asturias, SESPA, Oviedo, Spain.
  • Alptekin K; Biomedical Research Networking Centre in Mental Health (CIBERSAM), Madrid, Spain.
  • Saka MC; Department of Psychiatry, School of Medicine, University of Oviedo, Oviedo, Spain.
  • Arango C; Mental Health Services of Principado de Asturias, SESPA, Oviedo, Spain.
  • O'Donovan M; Biomedical Research Networking Centre in Mental Health (CIBERSAM), Madrid, Spain.
  • Rutten BPF; Department of Psychiatry, Hospital Clínico Universitario de Valencia, School of Medicine, Universidad de Valencia, INCLIVA, Valencia, Spain.
  • Guloksuz S; Biomedical Research Networking Centre in Mental Health (CIBERSAM), Madrid, Spain.
Psychol Med ; 50(11): 1884-1897, 2020 08.
Article en En | MEDLINE | ID: mdl-31414981
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Trastornos Psicóticos / Esquizofrenia / Herencia Multifactorial / Hermanos / Interacción Gen-Ambiente Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Psychol Med Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Trastornos Psicóticos / Esquizofrenia / Herencia Multifactorial / Hermanos / Interacción Gen-Ambiente Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Psychol Med Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos