MKP1 phosphatase is recruited by CXCL12 in glioblastoma cells and plays a role in DNA strand breaks repair.

Dedobbeleer, Matthias; Willems, Estelle; Lambert, Jeremy; Lombard, Arnaud; Digregorio, Marina; Lumapat, Paul Noel; Di Valentin, Emmanuel; Freeman, Stephen; Goffart, Nicolas; Scholtes, Felix; Rogister, Bernard

Dedobbeleer, Matthias; Willems, Estelle; Lambert, Jeremy; Lombard, Arnaud; Digregorio, Marina; Lumapat, Paul Noel; Di Valentin, Emmanuel; Freeman, Stephen; Goffart, Nicolas; Scholtes, Felix; Rogister, Bernard.

Afiliación

Dedobbeleer M; Laboratory of Nervous System Diseases and Therapy, GIGA-Neuroscience, University of Liège, Liège, Belgium.
Willems E; Laboratory of Nervous System Diseases and Therapy, GIGA-Neuroscience, University of Liège, Liège, Belgium.
Lambert J; Laboratory of Nervous System Diseases and Therapy, GIGA-Neuroscience, University of Liège, Liège, Belgium.
Lombard A; Laboratory of Nervous System Diseases and Therapy, GIGA-Neuroscience, University of Liège, Liège, Belgium.
Digregorio M; Department of Neurosurgery, CHU of Liège, Liège, Belgium.
Lumapat PN; Laboratory of Nervous System Diseases and Therapy, GIGA-Neuroscience, University of Liège, Liège, Belgium.
Di Valentin E; Laboratory of Nervous System Diseases and Therapy, GIGA-Neuroscience, University of Liège, Liège, Belgium.
Freeman S; Viral Vector Platform, GIGA Institute, University of Liège, Liège, Belgium.
Goffart N; Laboratory of Nervous System Diseases and Therapy, GIGA-Neuroscience, University of Liège, Liège, Belgium.
Scholtes F; The T&P Bohnenn Laboratory for Neuro-Oncology, Department of Neurosurgery, UMC Utrecht, Utrecht, The Netherlands.
Rogister B; Laboratory of Nervous System Diseases and Therapy, GIGA-Neuroscience, University of Liège, Liège, Belgium.

Carcinogenesis ; 41(4): 417-429, 2020 06 17.

Article en En | MEDLINE | ID: mdl-31504251

Asunto(s)

Biomarcadores de Tumor/metabolismo; Neoplasias Encefálicas/genética; Quimiocina CXCL12/metabolismo; Reparación del ADN; ADN/metabolismo; Fosfatasa 1 de Especificidad Dual/metabolismo; Glioblastoma/genética; Apoptosis; Biomarcadores de Tumor/genética; Neoplasias Encefálicas/metabolismo; Neoplasias Encefálicas/patología; Proliferación Celular; Quimiocina CXCL12/genética; ADN/genética; ADN/efectos de la radiación; Fosfatasa 1 de Especificidad Dual/genética; Regulación Neoplásica de la Expresión Génica; Glioblastoma/metabolismo; Glioblastoma/patología; Humanos; Fosforilación; Pronóstico; Transducción de Señal; Tasa de Supervivencia; Células Tumorales Cultivadas

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / ADN / Biomarcadores de Tumor / Glioblastoma / Reparación del ADN / Fosfatasa 1 de Especificidad Dual / Quimiocina CXCL12 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Carcinogenesis Año: 2020 Tipo del documento: Article País de afiliación: Bélgica

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