T cell-derived soluble glycoprotein GPIb&#945; mediates PGE<sub>2</sub> production in human monocytes activated with the vaccine adjuvant MDP.

Liu, Fengjie; Endo, Yukinori; Romantseva, Tatiana; Wu, Wells W; Akue, Adovi; Shen, Rong-Fong; Golding, Hana; Zaitseva, Marina

T cell-derived soluble glycoprotein GPIbα mediates PGE₂ production in human monocytes activated with the vaccine adjuvant MDP.

Liu, Fengjie; Endo, Yukinori; Romantseva, Tatiana; Wu, Wells W; Akue, Adovi; Shen, Rong-Fong; Golding, Hana; Zaitseva, Marina.

Afiliación

Liu F; Division of Viral Products, Food and Drug Administration, Silver Spring, MD 20993, USA.
Endo Y; Division of Viral Products, Food and Drug Administration, Silver Spring, MD 20993, USA.
Romantseva T; Division of Viral Products, Food and Drug Administration, Silver Spring, MD 20993, USA.
Wu WW; Facility for Biotechnology Resources, Food and Drug Administration, Silver Spring, MD 20993, USA.
Akue A; Flow Cytometry Core, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD 20993, USA.
Shen RF; Facility for Biotechnology Resources, Food and Drug Administration, Silver Spring, MD 20993, USA.
Golding H; Division of Viral Products, Food and Drug Administration, Silver Spring, MD 20993, USA.
Zaitseva M; Division of Viral Products, Food and Drug Administration, Silver Spring, MD 20993, USA. marina.zaitseva@fda.hhs.gov.

Sci Signal ; 12(602)2019 10 08.

Article en En | MEDLINE | ID: mdl-31594856

Asunto(s)

Acetilmuramil-Alanil-Isoglutamina/farmacología; Dinoprostona/metabolismo; Monocitos/efectos de los fármacos; Complejo GPIb-IX de Glicoproteína Plaquetaria/metabolismo; Linfocitos T/metabolismo; Adyuvantes Inmunológicos/farmacología; Animales; Calcio/metabolismo; Células Cultivadas; Medios de Cultivo Condicionados/farmacología; Femenino; Células HEK293; Humanos; Interleucina-1beta/genética; Interleucina-1beta/metabolismo; Interleucina-6/genética; Interleucina-6/metabolismo; Antígeno de Macrófago-1/genética; Antígeno de Macrófago-1/metabolismo; Ratones Noqueados; Monocitos/citología; Monocitos/metabolismo; Proteína Adaptadora de Señalización NOD2/metabolismo; Complejo GPIb-IX de Glicoproteína Plaquetaria/genética; Conejos; Transducción de Señal/efectos de los fármacos; Células THP-1

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Monocitos / Linfocitos T / Dinoprostona / Acetilmuramil-Alanil-Isoglutamina / Complejo GPIb-IX de Glicoproteína Plaquetaria Límite: Animals / Female / Humans Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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