Pityriasis alba: Possible associations with intestinal helminths and pathogenic protozoa.
Int J Clin Pract
; 74(2): e13441, 2020 Feb.
Article
en En
| MEDLINE
| ID: mdl-31633268
ABSTRACT
BACKGROUND:
The aetiology of pityriasis alba (PA) remains uncertain, and children are at risk for PA and intestinal parasites.AIM:
To determine the prevalence of intestinal parasites in PA patients and to evaluate their possible role in PA pathogenesis.METHODS:
Overall, 180 PA patients and 100 healthy individuals were enrolled. Intestinal parasites were diagnosed by triple coproscopy, and the total serum Immunoglobulin E (IgE) levels were determined by ELISA. PA patients with intestinal parasites were treated with conventional antiparasitic drugs. Patient response to antiparasitic therapy was evaluated after 6 weeks.RESULTS:
The prevalence of intestinal parasites in PA patients and controls was 60 ± 3.6% and 32 ± 4.6%, respectively (P < .0001). Regardless of the parasite species among the PA patients and control individuals, the total IgE levels were significantly higher in PA patients (P ≤ .05). The highest values of IgE were found in PA patients with Hymenolepis nana (641.7 ± 46.3 IU/mL). The total IgE level in PA patients with parasites decreased after antiparasitic therapy, but the reduction was only significant in patients with H. nana (P < .05). Complete disappearance of hypopigmented patches was observed after the elimination of H. nana, Giardia lamblia and Enterobius vermicularis in 65 ± 10.6%, 48.7 ± 8.0% and 33.3 ± 8.2% of cases, respectively. In total, a positive clinical response to antiparasitic therapy was achieved in 60 ± 4.7% of infected PA patients.CONCLUSION:
A positive clinical response to antiparasitic therapy indicates the role of intestinal parasites in PA pathogenesis. Parasitological examination is justified by the recovery of 60 ± 4.7% of infected PA patients after the elimination of intestinal parasites.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Pitiriasis
/
Heces
/
Helmintiasis
/
Helmintos
/
Parasitosis Intestinales
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Animals
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Int J Clin Pract
Asunto de la revista:
MEDICINA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Uzbekistán