A canine vaccine against Leptospira serovars Icterohaemorrhagiae, Canicola and Grippotyphosa provides cross protection against Leptospira serovar Copenhageni.
Vet Immunol Immunopathol
; 219: 109985, 2020 Jan.
Article
en En
| MEDLINE
| ID: mdl-31759261
ABSTRACT
Efficacy of the Leptospira components of multivalent vaccine DAPPi-L was previously demonstrated against virulent challenge with three serovars of Leptospira interrogans (Canicola, Icterohaemorrhagiae and Grippotyphosa) carried out 14 days after primary vaccination. In this study we demonstrate that this vaccine provides, two weeks after vaccination, an additional protection (prevention of mortality, clinical signs, renal infection, bacterial excretion, renal carriage and renal lesions) against fatal leptospirosis due to Leptospira interrogans serovar Copenhageni (serovar of major medical importance).
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Base de datos:
MEDLINE
Asunto principal:
Vacunas Bacterianas
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Vacunación
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Enfermedades de los Perros
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Protección Cruzada
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Leptospira interrogans
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Leptospirosis
Límite:
Animals
Idioma:
En
Revista:
Vet Immunol Immunopathol
Año:
2020
Tipo del documento:
Article