Elite Intratumoral T-cell Clonotypes (The 1%) Effect "Trickle-Down Cytotoxicity".
Clin Cancer Res
; 26(6): 1205-1207, 2020 03 15.
Article
en En
| MEDLINE
| ID: mdl-31919138
ABSTRACT
Careful study of T-cell clonal dynamics in patients with non-small cell lung cancer treated with neoadjuvant nivolumab suggests that successful trafficking of clones from a proliferative burst in the periphery to the tumor associates with major pathologic response. Integration of these findings with functional analysis may augment current therapeutic strategies.See related article by Zhang et al., p. 1327.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Carcinoma de Pulmón de Células no Pequeñas
/
Neoplasias Pulmonares
Límite:
Humans
Idioma:
En
Revista:
Clin Cancer Res
Asunto de la revista:
NEOPLASIAS
Año:
2020
Tipo del documento:
Article