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Remethylation of Dnmt3a-/- hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing.
Ketkar, Shamika; Verdoni, Angela M; Smith, Amanda M; Bangert, Celia V; Leight, Elizabeth R; Chen, David Y; Brune, Meryl K; Helton, Nichole M; Hoock, Mieke; George, Daniel R; Fronick, Catrina; Fulton, Robert S; Ramakrishnan, Sai Mukund; Chang, Gue Su; Petti, Allegra A; Spencer, David H; Miller, Christopher A; Ley, Timothy J.
Afiliación
  • Ketkar S; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Verdoni AM; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Smith AM; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Bangert CV; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Leight ER; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Chen DY; Division of Dermatology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Brune MK; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Helton NM; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Hoock M; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • George DR; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Fronick C; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63110.
  • Fulton RS; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63110.
  • Ramakrishnan SM; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Chang GS; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63110.
  • Petti AA; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Spencer DH; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63110.
  • Miller CA; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Ley TJ; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63110.
Proc Natl Acad Sci U S A ; 117(6): 3123-3134, 2020 02 11.
Article en En | MEDLINE | ID: mdl-31996479
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células de la Médula Ósea / Expresión Génica / Metilación de ADN / ADN (Citosina-5-)-Metiltransferasas Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células de la Médula Ósea / Expresión Génica / Metilación de ADN / ADN (Citosina-5-)-Metiltransferasas Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article