G-protein-coupled estrogen receptor activation upregulates interleukin-1 receptor antagonist in the hippocampus after global cerebral ischemia: implications for neuronal self-defense.

Bai, Ning; Zhang, Quanguang; Zhang, Wenli; Liu, Bin; Yang, Fang; Brann, Darrell; Wang, Ruimin

Bai, Ning; Zhang, Quanguang; Zhang, Wenli; Liu, Bin; Yang, Fang; Brann, Darrell; Wang, Ruimin.

Afiliación

Bai N; Neurobiology Institute of Medical Research Center, North China University of Science and Technology, Tangshan, 063210, Hebei, China.
Zhang Q; Department of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
Zhang W; Neurobiology Institute of Medical Research Center, North China University of Science and Technology, Tangshan, 063210, Hebei, China.
Liu B; First Department of Neurology, Hospital Affiliated to North China University of Science and Technology, Tangshan, 063000, Hebei, China.
Yang F; Neurobiology Institute of Medical Research Center, North China University of Science and Technology, Tangshan, 063210, Hebei, China.
Brann D; Department of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA. dbrann@augusta.edu.
Wang R; Neurobiology Institute of Medical Research Center, North China University of Science and Technology, Tangshan, 063210, Hebei, China. ruimin-wang@163.com.

J Neuroinflammation ; 17(1): 45, 2020 Feb 01.

Article en En | MEDLINE | ID: mdl-32007102

Asunto(s)

Isquemia Encefálica/metabolismo; Hipocampo/metabolismo; Proteína Antagonista del Receptor de Interleucina 1/metabolismo; Neuronas/metabolismo; Receptores Acoplados a Proteínas G/metabolismo; Animales; Apoptosis; Isquemia Encefálica/psicología; Región CA1 Hipocampal/metabolismo; Muerte Celular; Supervivencia Celular; Cognición; Femenino; Proteína Antagonista del Receptor de Interleucina 1/genética; Aprendizaje por Laberinto; Neuronas/patología; Ratas; Ratas Sprague-Dawley; Receptores Acoplados a Proteínas G/genética; Reconocimiento en Psicología; Factor de Transcripción ReIA/metabolismo

Palabras clave

G-protein-coupled estrogen receptor 1 (GPER/GPR30); Global cerebral ischemia; Inflammasome; Interleukin-1 receptor antagonist (IL1RA); NACHT-, LRR- and PYD-containing protein 3 (NLRP3)

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Isquemia Encefálica / Receptores Acoplados a Proteínas G / Proteína Antagonista del Receptor de Interleucina 1 / Hipocampo / Neuronas Límite: Animals Idioma: En Revista: J Neuroinflammation Asunto de la revista: NEUROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China

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