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Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the treatment of venous thromboembolism.
Solms, Alexander; Willmann, Stefan; Reinecke, Isabel; Spiro, Theodore E; Peters, Gary; Weitz, Jeffrey I; Mueck, Wolfgang; Garmann, Dirk; Schmidt, Stephan; Zhang, Liping; Fox, Keith A A; Berkowitz, Scott D.
Afiliación
  • Solms A; Clinical Pharmacometrics, Bayer AG, Berlin, Germany.
  • Willmann S; Clinical Pharmacometrics, Bayer AG, Wuppertal, Germany.
  • Reinecke I; Bayer AB, Solna, Sweden.
  • Spiro TE; Bayer U.S., LLC, Research & Development, Pharmaceuticals, 100 Bayer Boulevard, Whippany, NJ, 07981, USA.
  • Peters G; Janssen Research & Development, LLC, Raritan, NJ, USA.
  • Weitz JI; McMaster University and the Thrombosis & Atherosclerosis, Hamilton, ON, Canada.
  • Mueck W; Clinical Pharmacokinetics, Bayer AG, Wuppertal, Germany.
  • Garmann D; Clinical Pharmacometrics, Bayer AG, Wuppertal, Germany.
  • Schmidt S; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL, USA.
  • Zhang L; Janssen Research & Development, LLC, Raritan, NJ, USA.
  • Fox KAA; Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, UK.
  • Berkowitz SD; Bayer U.S., LLC, Research & Development, Pharmaceuticals, 100 Bayer Boulevard, Whippany, NJ, 07981, USA. scott.berkowitz@bayer.com.
J Thromb Thrombolysis ; 50(1): 1-11, 2020 Jul.
Article en En | MEDLINE | ID: mdl-32323191
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Monitoreo de Drogas / Ajuste de Riesgo / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Tromboembolia Venosa / Rivaroxabán Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: J Thromb Thrombolysis Asunto de la revista: ANGIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Monitoreo de Drogas / Ajuste de Riesgo / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Tromboembolia Venosa / Rivaroxabán Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: J Thromb Thrombolysis Asunto de la revista: ANGIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Alemania