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Pharmacokinetics, Safety, and Tolerability of Selonsertib, an Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitor, Following First-in-Human Single and Multiple Ascending Doses in Healthy Subjects.
Nelson, Cara H; Etchevers, Kim; Yi, Saili; Breckenridge, David; Hepner, Mischa; Patel, Uptal; Ling, John; Mathias, Anita.
Afiliación
  • Nelson CH; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA. cara.nelson@gilead.com.
  • Etchevers K; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA.
  • Yi S; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA.
  • Breckenridge D; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA.
  • Hepner M; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA.
  • Patel U; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA.
  • Ling J; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA.
  • Mathias A; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA, 94404, USA.
Clin Pharmacokinet ; 59(9): 1109-1117, 2020 09.
Article en En | MEDLINE | ID: mdl-32333325
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piridinas / Benzamidas / MAP Quinasa Quinasa Quinasa 5 / Imidazoles Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans Idioma: En Revista: Clin Pharmacokinet Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piridinas / Benzamidas / MAP Quinasa Quinasa Quinasa 5 / Imidazoles Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans Idioma: En Revista: Clin Pharmacokinet Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos