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Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Marchetto, Aruna; Ohmura, Shunya; Orth, Martin F; Knott, Maximilian M L; Colombo, Maria V; Arrigoni, Chiara; Bardinet, Victor; Saucier, David; Wehweck, Fabienne S; Li, Jing; Stein, Stefanie; Gerke, Julia S; Baldauf, Michaela C; Musa, Julian; Dallmayer, Marlene; Romero-Pérez, Laura; Hölting, Tilman L B; Amatruda, James F; Cossarizza, Andrea; Henssen, Anton G; Kirchner, Thomas; Moretti, Matteo; Cidre-Aranaz, Florencia; Sannino, Giuseppina; Grünewald, Thomas G P.
Afiliación
  • Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Colombo MV; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Arrigoni C; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
  • Bardinet V; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.
  • Saucier D; Department of Pediatrics, Division of Oncology and Hematology, Charité Berlin, Berlin, Germany.
  • Wehweck FS; Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, TX, USA.
  • Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Stein S; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Hölting TLB; Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
  • Amatruda JF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Cossarizza A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Henssen AG; Hopp-Children's Cancer Center (KiTZ), Heidelberg, Germany.
  • Kirchner T; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Moretti M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Cidre-Aranaz F; Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, TX, USA.
  • Sannino G; Children's Hospital of Los Angeles, Los Angeles, CA, USA.
  • Grünewald TGP; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Modena, Italy.
Nat Commun ; 11(1): 2423, 2020 05 15.
Article en En | MEDLINE | ID: mdl-32415069
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sarcoma de Ewing / Regulación Neoplásica de la Expresión Génica / Proteínas de Fusión Oncogénica / Estrés Oxidativo Límite: Adult / Animals / Child / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sarcoma de Ewing / Regulación Neoplásica de la Expresión Génica / Proteínas de Fusión Oncogénica / Estrés Oxidativo Límite: Adult / Animals / Child / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Alemania