Could the Inhibition of Endo-Lysosomal Two-Pore Channels (TPCs) by the Natural Flavonoid Naringenin Represent an Option to Fight SARS-CoV-2 Infection?

Filippini, Antonio; D'Amore, Antonella; Palombi, Fioretta; Carpaneto, Armando

Filippini, Antonio; D'Amore, Antonella; Palombi, Fioretta; Carpaneto, Armando.

Afiliación

Filippini A; Unit of Histology and Medical Embryology, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, SAPIENZA University of Rome, Rome, Italy.
D'Amore A; Unit of Histology and Medical Embryology, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, SAPIENZA University of Rome, Rome, Italy.
Palombi F; Unit of Histology and Medical Embryology, Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, SAPIENZA University of Rome, Rome, Italy.
Carpaneto A; Department of Earth, Environment and Life Sciences (DISTAV), University of Genoa, Genoa, Italy.

Front Microbiol ; 11: 970, 2020.

Article en En | MEDLINE | ID: mdl-32425923

Palabras clave

Naringenin; SARS - CoV; antiviral treatment; endo-lysosomal dysfunction; therapeutic targets; two-pore channel (TPC)

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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Front Microbiol Año: 2020 Tipo del documento: Article País de afiliación: Italia

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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Front Microbiol Año: 2020 Tipo del documento: Article País de afiliación: Italia