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A generic PBTK model implemented in the MCRA platform: Predictive performance and uses in risk assessment of chemicals.
Tebby, Cleo; van der Voet, Hilko; de Sousa, Georges; Rorije, Emiel; Kumar, Vikas; de Boer, Waldo; Kruisselbrink, Johannes W; Bois, Frédéric Y; Faniband, Moosa; Moretto, Angelo; Brochot, Céline.
Afiliación
  • Tebby C; INERIS, Unit Models for Ecotoxicology and Toxicology (METO), Verneuil-en-Halatte, France. Electronic address: cleo.tebby@ineris.fr.
  • van der Voet H; Wageningen University & Research, Biometris, Wageningen, Netherlands.
  • de Sousa G; INRAE, Toxalim, France.
  • Rorije E; RIVM, Centre for Safety of Substances and Products, Department for Consumers and Product Safety, P.O. Box 1, 3720, BA Bilthoven, Netherlands.
  • Kumar V; URV, Universitat Rovira i Virgili, C/ Països Catalans, nº 26, 43007, Tarragona (Tarragona- Catalonia), Spain.
  • de Boer W; Wageningen University & Research, Biometris, Wageningen, Netherlands.
  • Kruisselbrink JW; Wageningen University & Research, Biometris, Wageningen, Netherlands.
  • Bois FY; INERIS, Unit Models for Ecotoxicology and Toxicology (METO), Verneuil-en-Halatte, France.
  • Faniband M; Division of Occupational and Environmental Medicine, Faculty of Medicine, Lund University, Sweden.
  • Moretto A; Department of Biomedical and Clinical Sciences, Università degli Studi di Milano, Italy.
  • Brochot C; INERIS, Unit Models for Ecotoxicology and Toxicology (METO), Verneuil-en-Halatte, France.
Food Chem Toxicol ; 142: 111440, 2020 Aug.
Article en En | MEDLINE | ID: mdl-32473292
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sustancias Peligrosas / Toxicocinética / Modelos Biológicos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Food Chem Toxicol Año: 2020 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sustancias Peligrosas / Toxicocinética / Modelos Biológicos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Food Chem Toxicol Año: 2020 Tipo del documento: Article