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A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells.
Feng, Ling; Xie, Yusheng; Au-Yeung, Sung King; Hailu, Hagos Birhanu; Liu, Zhiyang; Chen, Qingxin; Zhang, Jie; Pang, Qiuxiang; Yao, Xi; Yang, Mengsu; Zhang, Liang; Sun, Hongyan.
Afiliación
  • Feng L; Cancer and Aging Research Institution, School of Life Science, Shandong University of Technology, China and Department of Chemistry and COSDAF (Centre of Super-Diamond and Advanced Films), City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China. yushengxie@outlook.com hongysun@ci
  • Xie Y; Department of Chemistry and COSDAF (Centre of Super-Diamond and Advanced Films), City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China. yushengxie@outlook.com hongysun@cityu.edu.hk and Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institute
  • Au-Yeung SK; Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institute of City University of Hong Kong, Shenzhen, 518057, P. R. China and Department of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, 83 Tat Chee Avenue, Kowlo
  • Hailu HB; Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institute of City University of Hong Kong, Shenzhen, 518057, P. R. China and Department of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, 83 Tat Chee Avenue, Kowlo
  • Liu Z; Department of Chemistry and COSDAF (Centre of Super-Diamond and Advanced Films), City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China. yushengxie@outlook.com hongysun@cityu.edu.hk and Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institute
  • Chen Q; Department of Chemistry and COSDAF (Centre of Super-Diamond and Advanced Films), City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China. yushengxie@outlook.com hongysun@cityu.edu.hk and Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institute
  • Zhang J; Department of Chemistry and COSDAF (Centre of Super-Diamond and Advanced Films), City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China. yushengxie@outlook.com hongysun@cityu.edu.hk and Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institute
  • Pang Q; Cancer and Aging Research Institution, School of Life Science, Shandong University of Technology, China.
  • Yao X; Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institute of City University of Hong Kong, Shenzhen, 518057, P. R. China and Department of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, 83 Tat Chee Avenue, Kowlo
  • Yang M; Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institute of City University of Hong Kong, Shenzhen, 518057, P. R. China and Department of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, 83 Tat Chee Avenue, Kowlo
  • Zhang L; Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institute of City University of Hong Kong, Shenzhen, 518057, P. R. China and Department of Biomedical Sciences, College of Veterinary Medicine and Life Sciences, City University of Hong Kong, 83 Tat Chee Avenue, Kowlo
  • Sun H; Department of Chemistry and COSDAF (Centre of Super-Diamond and Advanced Films), City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China. yushengxie@outlook.com hongysun@cityu.edu.hk and Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institute
Chem Commun (Camb) ; 56(60): 8480-8483, 2020 Jul 28.
Article en En | MEDLINE | ID: mdl-32588854
ABSTRACT
A rotor-based probe MRMP-1 was designed and synthesized. MRMP-1 can bind to plasma membranes very quickly and stably with remarkable fluorescence enhancement. It can be used to monitor the dynamic changes in cell membranes in real-time under stimuli conditions. Importantly, MRMP-1 is the first rotor-based fluorescent sensor to label exosomes in living cells.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Membrana Celular / Exosomas / Colorantes Fluorescentes Límite: Animals / Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Membrana Celular / Exosomas / Colorantes Fluorescentes Límite: Animals / Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article