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Physiological blood-brain transport is impaired with age by a shift in transcytosis.
Yang, Andrew C; Stevens, Marc Y; Chen, Michelle B; Lee, Davis P; Stähli, Daniel; Gate, David; Contrepois, Kévin; Chen, Winnie; Iram, Tal; Zhang, Lichao; Vest, Ryan T; Chaney, Aisling; Lehallier, Benoit; Olsson, Niclas; du Bois, Haley; Hsieh, Ryan; Cropper, Haley C; Berdnik, Daniela; Li, Lulin; Wang, Elizabeth Y; Traber, Gavin M; Bertozzi, Carolyn R; Luo, Jian; Snyder, Michael P; Elias, Joshua E; Quake, Stephen R; James, Michelle L; Wyss-Coray, Tony.
Afiliación
  • Yang AC; Department of Bioengineering, Stanford University School of Medicine, Stanford, CA, USA.
  • Stevens MY; ChEM-H, Stanford University, Stanford, CA, USA.
  • Chen MB; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Lee DP; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Stähli D; Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
  • Gate D; Department of Bioengineering, Stanford University School of Medicine, Stanford, CA, USA.
  • Contrepois K; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Chen W; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Iram T; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Zhang L; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Vest RT; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Chaney A; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Lehallier B; Chan Zuckerberg Biohub, Stanford, CA, USA.
  • Olsson N; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • du Bois H; Department of Chemical Engineering, Stanford, CA, USA.
  • Hsieh R; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Cropper HC; Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
  • Berdnik D; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Li L; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.
  • Wang EY; Calico Life Sciences LLC, South San Francisco, CA, USA.
  • Traber GM; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Bertozzi CR; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Luo J; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Snyder MP; Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
  • Elias JE; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Quake SR; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • James ML; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Wyss-Coray T; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
Nature ; 583(7816): 425-430, 2020 07.
Article en En | MEDLINE | ID: mdl-32612231
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Envejecimiento / Barrera Hematoencefálica / Transcitosis Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Envejecimiento / Barrera Hematoencefálica / Transcitosis Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos