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Predicted values for human total clearance of a variety of typical compounds with differently humanized-liver mouse plasma data.
Nakayama, Keigo; Kamimura, Hidetaka; Suemizu, Hiroshi; Yoneda, Nao; Nishiwaki, Megumi; Iwamoto, Kazuhiko; Mizunaga, Mari; Negoro, Tamotsu; Ito, Soichiro; Yamazaki, Hiroshi; Nomura, Yukihiro.
Afiliación
  • Nakayama K; Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., Takatsuki, Osaka, Japan. Electronic address: keigo.a.nakayama@jt.com.
  • Kamimura H; Laboratory Animal Research Department and Technical Service Department, Central Institute for Experimental Animals, Kawasaki, Kanagawa, Japan.
  • Suemizu H; Laboratory Animal Research Department and Technical Service Department, Central Institute for Experimental Animals, Kawasaki, Kanagawa, Japan.
  • Yoneda N; Laboratory Animal Research Department and Technical Service Department, Central Institute for Experimental Animals, Kawasaki, Kanagawa, Japan.
  • Nishiwaki M; Laboratory Animal Research Department and Technical Service Department, Central Institute for Experimental Animals, Kawasaki, Kanagawa, Japan; Technical Service Department, Central Institute for Experimental Animals, Kawasaki, Kanagawa, Japan.
  • Iwamoto K; Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., Takatsuki, Osaka, Japan.
  • Mizunaga M; Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., Takatsuki, Osaka, Japan.
  • Negoro T; Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., Takatsuki, Osaka, Japan.
  • Ito S; Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., Takatsuki, Osaka, Japan.
  • Yamazaki H; Showa Pharmaceutical University, Machida, Tokyo, Japan.
  • Nomura Y; Drug Metabolism & Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., Takatsuki, Osaka, Japan.
Drug Metab Pharmacokinet ; 35(4): 389-396, 2020 Aug.
Article en En | MEDLINE | ID: mdl-32690433
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Preparaciones Farmacéuticas / Hígado Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Drug Metab Pharmacokinet Asunto de la revista: FARMACOLOGIA / METABOLISMO Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Preparaciones Farmacéuticas / Hígado Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Drug Metab Pharmacokinet Asunto de la revista: FARMACOLOGIA / METABOLISMO Año: 2020 Tipo del documento: Article