Epigenetic regulation of apoptosis via the PARK7 interactome in peripheral blood mononuclear cells donated by tuberculosis patients vs. healthy controls and the response to treatment: A systems biology approach.

Vavougios, George D; Zarogiannis, Sotirios G; Krogfelt, Karen A; Stamoulis, George; Gourgoulianis, Konstantinos I

Vavougios, George D; Zarogiannis, Sotirios G; Krogfelt, Karen A; Stamoulis, George; Gourgoulianis, Konstantinos I.

Afiliación

Vavougios GD; Department of Neurology, Athens Naval Hospital, Deinokratous 70, 115 21, Athens, Greece; Department of Electrical and Computer Engineering, 37 Glavani - 28th October Street, Deligiorgi Building, 4th floor, 382 21, Volos, Greece. Electronic address: dantevavougios@hotmail.com.
Zarogiannis SG; Department of Pleural Physiology, Faculty of Medicine, University of Thessaly, BIOPOLIS, Mezourlo, 41500, Larisa, Greece.
Krogfelt KA; Department of Science and Environment, Molecular and Medical Biology, Roskilde University, Universitetsvej 1, 28A.1, DK-4000, Roskilde, Denmark.
Stamoulis G; Department of Electrical and Computer Engineering, 37 Glavani - 28th October Street, Deligiorgi Building, 4th floor, 382 21, Volos, Greece.
Gourgoulianis KI; Department of Respiratory Medicine, Faculty of Medicine, University of Thessaly, BIOPOLIS, Mezourlo, 41110, Larisa, Greece.

Tuberculosis (Edinb) ; 123: 101938, 2020 07.

Article en En | MEDLINE | ID: mdl-32741527

Asunto(s)

Apoptosis; Epigénesis Genética; Leucocitos Mononucleares/enzimología; Mycobacterium tuberculosis/patogenicidad; Proteína Desglicasa DJ-1/genética; Biología de Sistemas; Tuberculosis/enzimología; Estudios de Casos y Controles; Estudios Transversales; Bases de Datos Genéticas; Perfilación de la Expresión Génica; Redes Reguladoras de Genes; Interacciones Huésped-Patógeno; Humanos; Leucocitos Mononucleares/microbiología; Leucocitos Mononucleares/patología; Estudios Longitudinales; Proteína Desglicasa DJ-1/metabolismo; Mapas de Interacción de Proteínas; Transducción de Señal; Transcripción Genética; Transcriptoma; Tuberculosis/sangre; Tuberculosis/genética; Tuberculosis/microbiología

Palabras clave

Mycobacteria; Parkinson's; Pathway; Systems; Tuberculosis; biology; d; enrichment; isease

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tuberculosis / Leucocitos Mononucleares / Apoptosis / Epigénesis Genética / Biología de Sistemas / Proteína Desglicasa DJ-1 / Mycobacterium tuberculosis Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Tuberculosis (Edinb) Año: 2020 Tipo del documento: Article

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