Safety and tolerability of topical polyhexamethylene biguanide: a randomised clinical trial in healthy adult volunteers.

Papa, Vincenzo; van der Meulen, Ivanka; Rottey, Sylvie; Sallet, Guy; Overweel, Jolanda; Asero, Nino; Minassian, Darwin C; Dart, John K G

Papa, Vincenzo; van der Meulen, Ivanka; Rottey, Sylvie; Sallet, Guy; Overweel, Jolanda; Asero, Nino; Minassian, Darwin C; Dart, John K G.

Afiliación

Papa V; SIFI S.p.A., 36, via Ercole Patti, 95025 Lavinaio (Catania), Italy, Lavinaio, Italy.
van der Meulen I; Amsterdam UMC Locatie AMC, Amsterdam, Netherlands.
Rottey S; DRUG Research Unit, Ghent, Belgium.
Sallet G; Ooginstituut, Aalst, Belgium.
Overweel J; PSR Group BV, Hoofddorp, Netherlands.
Asero N; SIFI SpA, Catania, Italy.
Minassian DC; Epivision Ophthalmic Epidemiology Consultants, Penn, UK.
Dart JKG; Corneal & External Disease, Moorfields Eye Hospital NHS Foundation Trust, London, UK j.dart@ucl.ac.uk.

Br J Ophthalmol ; 106(2): 190-196, 2022 02.

Article en En | MEDLINE | ID: mdl-33239413

Asunto(s)

Queratitis por Acanthamoeba; Biguanidas; Queratitis por Acanthamoeba/tratamiento farmacológico; Adulto; Biguanidas/efectos adversos; Voluntarios Sanos; Humanos; Estudios Prospectivos

Palabras clave

Clinical Trial; Cornea; Drugs; Infection; Treatment Medical

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Biguanidas / Queratitis por Acanthamoeba Tipo de estudio: Clinical_trials / Observational_studies / Risk_factors_studies Límite: Adult / Humans Idioma: En Revista: Br J Ophthalmol Año: 2022 Tipo del documento: Article País de afiliación: Italia

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