[Therapeutic options to reduce arterial stiffness in chronic kidney disease].
G Ital Nefrol
; 37(6)2020 Dec 07.
Article
en It
| MEDLINE
| ID: mdl-33295707
ABSTRACT
Chronic kidney disease is associated with an increased cardiovascular risk. Several uremic toxins are also vascular toxins and may contribute to the increase of the cardiovascular risk through the development of aortic stiffening. In this process, oxidative stress and endothelial dysfunction play an important role. Considering that aortic stiffness is a known cardiovascular risk factor and a vascular biomarker involved in the development of chronic cardiac dysfunction, and that the reduction of aortic stiffness is associated with an improved survival of patients with end-stage kidney disease, we aim at reviewing the therapeutic options to reduce aortic stiffness and potentially the cardiovascular risk.
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Base de datos:
MEDLINE
Asunto principal:
Insuficiencia Renal Crónica
/
Rigidez Vascular
/
Fallo Renal Crónico
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
Idioma:
It
Revista:
G Ital Nefrol
Asunto de la revista:
NEFROLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Italia