AMPK signaling mediates synphilin-1-induced hyperphagia and obesity in <i>Drosophila</i>.

Liu, Jingnan; Wang, Xiaobo; Ma, Rui; Li, Tianxia; Guo, Gongbo; Ning, Bo; Moran, Timothy H; Smith, Wanli W

AMPK signaling mediates synphilin-1-induced hyperphagia and obesity in Drosophila.

Liu, Jingnan; Wang, Xiaobo; Ma, Rui; Li, Tianxia; Guo, Gongbo; Ning, Bo; Moran, Timothy H; Smith, Wanli W.

Afiliación

Liu J; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.
Wang X; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Ma R; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.
Li T; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.
Guo G; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Ning B; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Moran TH; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Smith WW; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA wsmith60@jhmi.edu.

J Cell Sci ; 134(3)2021 02 05.

Article en En | MEDLINE | ID: mdl-33443093

Asunto(s)

Proteínas Quinasas Activadas por AMP; Proteínas Portadoras/genética; Drosophila; Hiperfagia; Proteínas del Tejido Nervioso/genética; Obesidad; Proteínas Quinasas Activadas por AMP/genética; Proteínas Quinasas Activadas por AMP/metabolismo; Animales; Animales Modificados Genéticamente; Drosophila/genética; Drosophila/metabolismo; Humanos; Hiperfagia/genética; Obesidad/genética; Transducción de Señal/genética

Palabras clave

AMPK; Energy homeostasis; Hyperphagia; Obesity; Synphilin-1

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Portadoras / Hiperfagia / Drosophila / Proteínas Quinasas Activadas por AMP / Proteínas del Tejido Nervioso / Obesidad Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Cell Sci Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google